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What is Combiflam?

Combiflam Cream contains Camphor, Menthol, and Methyl Salicylate as active ingredients.
Combiflam Cream works by temporarily relieving minor pain; inhibiting prostaglandin formation; lowering the histamine H1 and muscarinic M3 receptor-mediated bronchoconstriction; suppressing the mitochondrial respiration; activating the activities of hepatic enzymes;
Detailed information related to Combiflam Cream's uses, composition, dosage, side effects and reviews is listed below.

Combiflam Cream Uses

Combiflam Cream Working, Mechanism of Action and Pharmacology

Combiflam Cream improves the patient's condition by performing the following functions:
  • Temporarily relieving minor pain.
  • Inhibiting prostaglandin formation.
  • Lowering the histamine H1 and muscarinic M3 receptor-mediated bronchoconstriction; suppressing the mitochondrial respiration; activating the activities of hepatic enzymes.
References: 1, 2, 3

Combiflam Cream - Composition and Active Ingredients

Combiflam Cream is composed of the following active ingredients (salts)
Please note that this medicine may be available in various strengths for each active ingredient listed above.

Combiflam Cream - Side-effects

The following is a list of possible side-effects that may occur from all constituting ingredients of Combiflam Cream. This is not a comprehensive list. These side-effects are possible, but do not always occur. Some of the side-effects may be rare but serious. Consult your doctor if you observe any of the following side-effects, especially if they do not go away.
If you notice other side-effects not listed above, contact your doctor for medical advice. You may also report side-effects to your local food and drug administration authority.
References: 4, 5, 6
Learn more: Side-effects

Combiflam Cream - Precautions & How to Use

Before using this drug, inform your doctor about your current list of medications, over the counter products (e.g. vitamins, herbal supplements, etc.), allergies, pre-existing diseases, and current health conditions (e.g. pregnancy, upcoming surgery, etc.). Some health conditions may make you more susceptible to the side-effects of the drug. Take as directed by your doctor or follow the direction printed on the product insert. Dosage is based on your condition. Tell your doctor if your condition persists or worsens. Important counseling points are listed below.
  • Blood dyscrasias
  • Breastfeeding
  • Candidiasis
  • Darkening of tongue
  • Pregnancy
  • Pregnant, planning to become pregnant or breastfeeding
References: 3

Where to Buy Combiflam Cream

Click here to find nearby pharmacies/medical stores where you can buy Combiflam Cream.

Combiflam Cream - Drug Interactions

If you use other drugs or over the counter products at the same time, the effects of Combiflam Cream may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Combiflam Cream may interact with the following drugs and products:
  • Alcohol
  • Anisindione
  • Anisindione Coumadin
  • Dicumarol
  • Fresh crataegus berries
  • Jantoven
References: 1, 3
Learn more: Interactions

Combiflam Cream - Contraindications

Hypersensitivity to Combiflam Cream is a contraindication. In addition, Combiflam Cream should not be used if you have the following conditions:
References: 3
Learn more: Contraindications

Combiflam Cream - Frequently asked Questions

  • Is Combiflam Cream safe to consume or apply when pregnant?
    • Menthol: Please consult with your doctor for case-specific recommendations.
    • Methyl Salicylate: Please consult with your doctor for case-specific recommendations.
    • Camphor: Please consult with your doctor for case-specific recommendations.
    References: 3
  • Is Combiflam Cream safe while breastfeeding?
    • Menthol: Please discuss the risks and benefits with your doctor.
    • Methyl Salicylate: Please discuss the risks and benefits with your doctor.
    • Camphor: Please discuss the risks and benefits with your doctor.
  • Can Combiflam Cream be used for back pain and hemorrhoids?
    Yes, back pain and hemorrhoids are among the most common reported uses for Combiflam Cream. Please do not use Combiflam Cream for back pain and hemorrhoids without consulting first with your doctor. Click here to find out what other patients report as common uses for Combiflam Cream.
  • Is it safe to drive or operate heavy machinery when consuming?
    If you experience drowsiness, dizziness, hypotension or a headache as side-effects when using Combiflam Cream medicine then it may not be safe to drive a vehicle or operate heavy machinery. One should not drive a vehicle if using the medicine makes you drowsy, dizzy or lowers your blood-pressure extensively. Pharmacists also advise patients not to drink alcohol with medicines as alcohol intensifies drowsiness side-effects. Please check for these effects on your body when using Combiflam Cream. Always consult with your doctor for recommendations specific to your body and health conditions.
  • Is this medicine or product addictive or habit forming?
    Most medicines don't come with a potential for addiction or abuse. Usually, government's categorizes medicines that can be addictive as controlled substances. Examples include schedule H or X in India and schedule II-V in the US. Please consult the product package to make sure that the medicine does not belong to such special categorizations of medicines. Lastly, do not self-medicate and increase your body's dependence to medicines without the advice of a doctor.
  • Can it be stopped immediately or do I have to slowly ween off consumption?
    Some medicines need to be tapered or cannot be stopped immediately because of rebound effects. Please consult with your doctor for recommendations specific to your body, health and other medications that you may be using.

Other important Information on Combiflam Cream

Missing a dose

In case you miss a dose, use it as soon as you notice. If it is close to the time of your next dose, skip the missed dose and resume your dosing schedule. Do not use extra dose to make up for a missed dose. If you are regularly missing doses, consider setting an alarm or asking a family member to remind you. Please consult your doctor to discuss changes in your dosing schedule or a new schedule to make up for missed doses, if you have missed too many doses recently.
References: 7, 8, 9, 10

Overdosage of Combiflam Cream

  • Do not use more than prescribed dose. Taking more medication will not improve your symptoms; rather they may cause poisoning or serious side-effects. If you suspect that you or anyone else who may have overdosed of Combiflam Cream, please go to the emergency department of the closest hospital or nursing home. Bring a medicine box, container, or label with you to help doctors with necessary information.
  • Do not give your medicines to other people even if you know that they have the same condition or it seems that they may have similar conditions. This may lead to overdosage.
  • Please consult your physician or pharmacist or product package for more information.
References: 11, 12, 13

Storage of Combiflam Cream

  • Store medicines at room temperature, away from heat and direct light. Do not freeze medicines unless required by package insert. Keep medicines away from children and pets.
  • Do not flush medications down the toilet or pour them into drainage unless instructed to do so. Medication discarded in this manner may contaminate the environment. Please consult your pharmacist or doctor for more details on how to safely discard Combiflam Cream.
References: 14, 15, 16, 17

Expired Combiflam Cream

  • Taking a single dose of expired Combiflam Cream is unlikely to produce an adverse event. However, please discuss with your primary health provider or pharmacist for proper advice or if you feel unwell or sick. Expired drug may become ineffective in treating your prescribed conditions. To be on the safe side, it is important not to use expired drug. If you have a chronic illness that requires taking medicine constantly such as heart condition, seizures, and life-threatening allergies, you are much safer keeping in touch with your primary health care provider so that you can have a fresh supply of unexpired medications.
References: 18, 19

Dosage Information

Please consult your physician or pharmacist or refer to product package.

Combiflam Cream - Packages and Strengths

Combiflam Cream is available in the following packages and strengths
Combiflam Cream - Packages: 30GM Cream, 30 gm, 15GM Cream
Combiflam Cream - Strengths: 30GM

Combiflam Cream - Manufacturers

The medicine is manufactured by the following companies
  • Sanofi Aventis
  • Sanofi India

Combiflam Cream - Demographic Information


  1. Pubchem MENTHOL - Accessed: October 12, 2016.
  2. Clin Ther. 2010 Jan;32(1):34-43. doi: 10.1016/j.clinthera.2010.01.016. Efficacy and safety profile of a topical methyl salicylate and menthol patch in adult patients with mild to moderate muscle strain: a randomized, double-blind, parallel-group, placebo-controlled, multicenter study. - Accessed: October 12, 2016.
  3. Paolo Zuccarini, Giulio Soldani Camphor: benefits and risks of a widely used natural product - Accessed: October 12, 2016.
  4. Pubchem l-Menthol - Accessed: October 12, 2016.
  5. Clin Cosmet Investig Dermatol. 2015; 8: 455_461. Published online 2015 Aug 26. doi: 10.2147/CCID.S84765 PMCID: PMC4554394 Salicylic acid as a peeling agent: a comprehensive review - Accessed: October 12, 2016.
  6. Church, John (1797). An inaugural dissertation on camphor: submitted to the examination of the Rev. John Ewing, S.S.T.P. provost ; the trustees & medical faculty of the University of Pennsylvania, on the 12th of May, 1797 ; for the degree of Doctor of Medicine. University of Philadelphia: Printed by John Thompson. Retrieved January 18, 2013. - Accessed: October 12, 2016. (Accessed on 10/16/16)
  7. NHS Choices. What should I do if I miss a dose of antibiotics? - Accessed: July 14, 2016.
  8. Ever Miss a Dose of Your Medicine? - Accessed: July 3, 2016.
  9. Cancer.Net (2014). The Importance of Taking Your Medication Correctly - Accessed: July 3, 2016.
  10. Schachter, S.C., Shafer, P. O. &; Sirven, J.I. (2013). Missed Medicines. Epilepsy Foundation - Accessed: May 28, 2016.
  11. National Institute of Drug Abuse (2010). Prescription Drugs: Abuse and Addiction. Report Research Series - Accessed: July 21, 2016.
  12. eMedicinehealth (2016). Drug Overdose Overview - Accessed: July 21, 2016.
  13. Centers for Disease Control and Prevention (2010). Unintentional drug poisoning in the United States - Accessed: July 21, 2016.
  14. Centers for Disease Control and Prevention. December 12, 2011. Put your medicines up and away and out of sight - Accessed: June 10, 2016.
  15. The Center for Improving Medication Management and the National Council on Patient Information and Education. The quick scoop: medicines and your family: safely storing and disposing of medicines - Accessed: June 10, 2016.
  16. U.S. Food and Drug Administration. December 24, 2013. How to dispose of unused medications - Accessed: June 10, 2016.
  17. World Health Organization: Information sheet: Pharmaceuticals in drinking-water - Accessed: July 1, 2016.
  18. Lyon, R. C., Taylor, J. S., Porter, D. A., et al. (2006) Stability profiles of drug products extended beyond labeled expiration dates. Journal of Pharmaceutical Sciences; 95:1549-60 - Accessed: July 3, 2016.
  19. Harvard Medical School (2016). Drug Expiration Dates - Do They Mean Anything? - Accessed: May 1, 2016.

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APA Style Citation

  • Combiflam Cream - Uses, Side-effects, Reviews, and Precautions - Sanofi Aventis - Tablet Wise - India. (n.d.). Retrieved April 29, 2017, from

MLA Style Citation

  • "Combiflam Cream - Uses, Side-effects, Reviews, and Precautions - Sanofi Aventis - Tablet Wise - India" N.p., n.d. Web. 29 Apr. 2017.

Chicago Style Citation

  • "Combiflam Cream - Uses, Side-effects, Reviews, and Precautions - Sanofi Aventis - Tablet Wise - India" Tabletwise. Accessed April 29, 2017.

Alternate forms of Combiflam Cream

Last updated date

This page was last updated on 3/24/2017.
This page provides information for Combiflam Cream in English.
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