Intelligence » Leukemia » Last Week

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Vitamin C may stop leukemia from progressing

Thursday, August 17, 2017 -- New research finds that high-dose vitamin C can genetically 'reprogram' leukemic cells to mature and die normally, instead of replicating to cause cancer.

FDA approves Pfizer's drug for rare blood cancer

Thursday, August 17, 2017 -- (Reuters) - The U.S. Food and Drug Administration (FDA) said on Thursday it approved Pfizer Inc's rare blood cancer drug, Besponsa, with a boxed warning.

Venetoclax in Patients with Previously Treated Chronic Lymphocytic Leukemia

Tuesday, August 15, 2017 -- Venetoclax is the first BCL2 inhibitor to enter routine clinical practice. It is an orally bioavailable small molecule that binds BCL2 very specifically. Acting as a pharmacologic mimic of the proteins that initiate apoptosis (a so-called BH3 mimetic), venetoclax rapidly induces apoptosis in chronic lymphocytic leukemia (CLL) cells, which express high levels of BCL2 and rely on it to maintain their survival. As a single agent, daily venetoclax treatment induced durable responses in 79% of patients with relapsed or refractory CLL or small lymphocytic lymphoma in a phase I study, including complete remissions in 20% of patients. Its use was approved by the FDA in April 2016 for patients with previously treated del(17p) CLL on the basis of a

Findings pave way for three-drug combination treatment for childhood leukemia

Monday, August 14, 2017 -- The regimen devised by UCLA researchers has proven to kill cancer cells and eradicate acute lymphoblastic leukemia in mouse models.

H3 Biomedicine gets FDAorphan drug status for acute myelogenous leukemia treatment

Tuesday, August 15, 2017 -- The US Food and Drug Administration (FDA) has granted orphan drug designation for H3 Biomedicine's H3B-8800, its lead clinical compound for the treatment of patients with Acute Myelogenous Leukemia (AML) and Chronic Myelomonocytic Leukemia (CMML).

CAR T Cell Therapy for Acute Lymphoblastic Leukemia: An Evolutionary Perspective

Wednesday, August 16, 2017 -- Enthusiasm for the CAR T cell approach may redirect rather than augment other possibly safer, more effective, evolutionarily informed approaches to cancer therapy.

Non-Hodgkin Lymphoma (NHL) Treatment Regimens: Adult T-Cell Leukemia/Lymphoma

Monday, August 14, 2017 -- Get the most up-to-date treatment regimens for adult T-cell leukemia/lymphoma (a non-Hodgin leukemia), such as zidovudine + alpha-interferon.

Leukemia: Mushroom protein could be used in future treatments

Sunday, August 13, 2017 -- A protein found in the edible mushroom commonly known as "shaggy ink cap" has the potential to kill leukemia T cells, a new study suggests.