A study conducted at the University of Texas Health Science Center at San Antonio is a stepping stone to delay aging in people.
This study was published in the Science Daily on January 7th, 2019.
This anti-aging strategy has passed the first trial done on 14 volunteers. The participants were given the drugs to kill off toxic and old cells in the body.
The study was done on people who had lung disease. It has been said to be the first attempt to develop the analytics drug. This drug clears toxic cells in aged bodies. The researchers have claimed it to be a strategy to delay aging in healthy people.
The patients were given two pills named leukemia drug dasatinib along with a supplement called quercetin that could help in getting rid of aged cells. The patients didn't suffer any serious side-effects from the drugs.
The 14 participants were suffering from a fatal lung disease called idiopathic pulmonary fibrosis. It was found that 9 doses of those two pills for three weeks improved the condition of patients. It developed the ability in patients to walk more in the same time period.
James Kirkland, who helped in the trial said, “This gives us to some extent a green light to go on to larger trials. People should simply not be taking these drugs outside the context of a supervised clinical trial.”
Judith Campisi, a professor at the Buck Institute for Research on Aging in Novato, California said, “My worry is we should not leap into this too fast because if there’s a mistake or something we don’t understand, it could set the field back.”
Many pharmacy companies are finding their business in manufacturing this drug. A company called Unity Biotechnology of California has started developing the two analytic drugs.
This drug is injected into the knees of people. These drugs are aimed at senescent cells. Senescent cells lose the ability to split but remain proficient of emitting out strong chemical signals.
It has been stated that these cells are involved in the process of aging. It will be beneficial to remove these cells as it will promote healthy aging and will lead to avoid diseases of aging.
In idiopathic pulmonary fibrosis disease, senescent cells grow up in the lungs. In some tests performed on the mice, a blend of dasatinib and quercetin has worked to eliminate such cells. It also improves the health of the animals but it didn’t enhance their life.
The researchers are now looking forward to starting their trials with people having some serious diseases. It has been said that the burden of senescent cells can be reduced but it should not be totally removed.
Some researchers have already begun their trial in 15 other lung patients as well as 20 patients with chronic kidney disease.