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Clinical Index of Stable Febrile Neutropenia (CISNE)

ECOG PS 2 = Capable of all self care, but no work activities, out of bed >50% of day
<2 0
≥2 2
Stress-induced hyperglycemia
Initial blood glucose ≥121 mg/dL (6.7 mmol/L), or ≥250 mg/dL (13.9 mmol/L) in diabetics or if on steroids
No 0
Yes 2
COPD diagnosis on therapy with ≥1 of the following: steroids, supplemental O₂, bronchodilators
No 0
Yes 1
Cardiovascular disease history
Chronic heart conditions (e.g., cor pulmonale, heart failure, cardiomyopathy, hypertensive heart disease, arrhythmias, valvular disease, other structural malformations), EXCLUDING history of single uncomplicated episode of AFib
No 0
Yes 1
NCI mucositis grade ≥2
Painful erythema, edema, or ulcers, but eating/swallowing possible
No 0
Yes 1
≥200/µL 0
<200/µL 1


Result Interpretation

Ranges Ranges

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