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Modified Fatigue Impact Scale (MFIS)

Calculators  Neurology
It is considered as multidimensional scale which is used to analyse different aspects of fatigue by assessing impact on physical, psychosocial functioning and cognitive.
Less Active
Never 0
Rarely 1
Sometimes 2
Often 3
Almost Always 4
Trouble in paying attention
Never 0
Rarely 1
Sometimes 2
Often 3
Almost Always 4
Inability to focus
Never 0
Rarely 1
Sometimes 2
Often 3
Almost Always 4
Uncoordinated Clumsiness
Never 0
Rarely 1
Sometimes 2
Often 3
Almost Always 4
Forgetfulness
Never 0
Rarely 1
Sometimes 2
Often 3
Almost Always 4
Are you pacing youself from physical activities
Never 0
Rarely 1
Sometimes 2
Often 3
Almost Always 4
Depleted Motivation to do physical activities
Never 0
Rarely 1
Sometimes 2
Often 3
Almost Always 4
Limited interest in social activities
Never 0
Rarely 1
Sometimes 2
Often 3
Almost Always 4
Restricted ability to work apart from home
Never 0
Rarely 1
Sometimes 2
Often 3
Almost Always 4
Difficulty in long term management of physical activities
Never 0
Rarely 1
Sometimes 2
Often 3
Almost Always 4
Inability to take decisions
Never 0
Rarely 1
Sometimes 2
Often 3
Almost Always 4
Depleted Motivation to think properly
Never 0
Rarely 1
Sometimes 2
Often 3
Almost Always 4
Muscle Weakness
Never 0
Rarely 1
Sometimes 2
Often 3
Almost Always 4
Physical Discomfort
Never 0
Rarely 1
Sometimes 2
Often 3
Almost Always 4
Inability to perform thoughtful tasks
Never 0
Rarely 1
Sometimes 2
Often 3
Almost Always 4
Difficulty in organizing tasks
Never 0
Rarely 1
Sometimes 2
Often 3
Almost Always 4
Difficulty in completing physical tasks
Never 0
Rarely 1
Sometimes 2
Often 3
Almost Always 4
Difficulty in thinking
Never 0
Rarely 1
Sometimes 2
Often 3
Almost Always 4
Troubled Concentration
Never 0
Rarely 1
Sometimes 2
Often 3
Almost Always 4
Reduction in physical activity
Never 0
Rarely 1
Sometimes 2
Often 3
Almost Always 4
Adequate rest for longer period
Never 0
Rarely 1
Sometimes 2
Often 3
Almost Always 4
Result:

Background

Measured Factor
It measures the severity of fatigue and is also used for longitudinal tracking of a patient with multiple sclerosis associated fatigue.
Measured Factor Disease
  • Fatigue in patients with multiple sclerosis
  • Depression
Measured Factor Detail
The MFIS is used in a comparative analysis | The scale is taking depression into consideration
Speciality
Neurologist
Body System
Neurology
Formula
Total = Physical + Cognitive + Psychosocial
Measured Factor High Impact
  • There are total 86 points which further are divided into 3 parts consisting Physical-36, Cognitive-40, Pyschosocial-8

Result Interpretation

Ranges Ranges
Test Limitations
Further studies are warranted in order to identify what a change in MFIS score indicates on measure of quality of life in the physical and cognitive domains.
References: 3

Studies

Study Validation 1
The aim of this study was to compare the performance of the Fatigue Severity Scale (FSS) and the Modified Fatigue Impact Scale (MFIS) by measuring the frequency of fatigue in multiple sclerosis (MS) patients and in healthy subjects. A total of 354 (231 MS patients and 123 HC) subjects were recruited in the study. Assessment of fatigue was done by using the FSS and MFIS. Beck Depression Inventory (BDI) was used to measure depression and disability was measured by Expanded Disability Status Scale (EDSS) Results showed that 55% of MS patients and 13% of HC were fatigued.  The global MFIS was in correlation with FSS scores. This study concluded that both the scales were correlated with each other however MFIS is better predictor of fatigue in MS patients
References: 4
Study Validation 2
This study was conducted in the 43 patients with multiple sclerosis (MS). The aim of the study was to validate the Fatigue Severity Scale (FSS), Modified Fatigue Impact Scale (MFIS), and Checklist Individual Strength (CIS20R) in patients with multiple sclerosis (MS). The Intraclass Correlation Coefficients (ICCs), analysis by Bland and Altman, the smallest detectable change (SDC) and the minimal detectable change (MDC) were evaluated in patients. Results showed that according to Bland and Altman analysis there was insignificant difference between assessments. ICCs were in range from 0.76 (FSS), to 0.85 (MFIS) to 0.81 (CIS20R). Study concluded that all three scales showed good test retest reliability but further studies are warranted to improve the fatigue questionnaires.
References: 5
Study Validation 3
The aim of the study was to validate the Modified Fatigue Impact Scale (MFIS) in patients with mild to moderate traumatic brain injury (TBI). A total 106 patients with mild to moderate TBI were involved in the study. Various procedures and tests examined in the study were factor structure, internal consistency, convergent validity, sensitivity, and specificity of the MFIS. Results showed that MFIS total scale had a high internal consistency of MFIS and strong convergent validity which were measured. Accuracy of MFIS score was good to excellent as analyzed by Receiver operating characteristic curve. This study concluded that MFIS tool is a validated measure for evaluating the impact of fatigue on cognitive and physical functioning in subjects with mild to moderate TBI.
References: 6
Study Additional 1
The aim of the study was to validate the Modified Fatigue Impact Scale (MFIS) in patients with mild to moderate traumatic brain injury (TBI). A total 106 patients with mild to moderate TBI were involved in the study. Various procedures and tests examined in the study were factor structure, internal consistency, convergent validity, sensitivity, and specificity of the MFIS. Results showed that MFIS total scale had a high internal consistency of MFIS and strong convergent validity which were measured. Accuracy of MFIS score was good to excellent as analyzed by Receiver operating characteristic curve. This study concluded that MFIS tool is a validated measure for evaluating the impact of fatigue on cognitive and physical functioning in subjects with mild to moderate TBI.
References: 7
Study Additional 2
The objective of the study was to determine the validity, reliability and sensitiveness of the Modified Fatigue Impact Scale. 51 randomly selected patients with multiple sclerosis (MS) and 20 healthy subjects as control were involved in the study. The Modified Fatigue Impact Scale (MFIS), the Fatigue Severity Scale (FSS) and the fatigue subscale of Guy's Neurological Disability Scale (GNDS) were used to analyze the degree of fatigue in subjects. MFIS scale was able to separate individuals with MS from controls, and subjects with fatigue from the non-fatigued group. This study concludes that MFIS moderately correlates with FSS and is valid, reliable and sensitive instrument to measure the impact of fatigue due to MS in daily life.
References: 8
Study Additional 3
This pilot study was conducted on 15 subjects suffering from multiple sclerosis (MS) and 15 subjects with other chronic illnesses (as controls). MFIS questionnaire was filled by the subjects twice with a three-day interval. Results showed a good correlation among the scores of 2 measurements. MFIS is a valid and reliable model for assessing fatigue in MS patients
References: 9

References

  1. Fisk JD, Pontefract A, Ritvo PG, Archibald CJ, Murray TJ. The impact of fatigue on patients with multiple sclerosis. Can J Neurol Sci. 1994 Feb;21(1):9-14
  2. Tellez N et al. Does the Modified Fatigue Impact Scale offer a more comprehensive assessment of fatigue in MS? Mult Scler 2005;11(2):198– 202
  3. Larson RD. Psychometric properties of the modified fatigue impact scale. Int J MS Care. 2013;15(1):15-20.
  4. Téllez N, Río J, Tintoré M, Nos C, Galán I, Montalban X. Does the Modified Fatigue Impact Scale offer a more comprehensive assessment of fatigue in MS?. Mult Scler. 2005;11(2):198-202.
  5. Rietberg MB, Van wegen EE, Kwakkel G. Measuring fatigue in patients with multiple sclerosis: reproducibility, responsiveness and concurrent validity of three Dutch self-report questionnaires. Disabil Rehabil. 2010;32(22):1870-6.
  6. Schiehser DM, Delano-wood L, Jak AJ, Matthews SC, Simmons AN, Jacobson MW, et al. Validation of the Modified Fatigue Impact Scale in mild to moderate traumatic brain injury. J Head Trauma Rehabil. 2015;30(2):116-21.
  7. Kos D, Kerckhofs E, Carrea I, Verza R, Ramos M, Jansa J. Evaluation of the Modified Fatigue Impact Scale in four different European countries. Mult Scler. 2005;11(1):76-80.
  8. Kos D, Kerckhofs E, Nagels G, D'Hooghe BD, Duquet W, Duportail M, et al. Assessing fatigue in multiple sclerosis: Dutch modified fatigue impact scale. Acta Neurol Belg. 2003;103(4):185-91.
  9. Harirchian MH, Nasergivechi S, Maddah M, Meysamie A, Amini H, Shandiz EE, et al. Evaluation of the Persian version of modified fatigue impact scale in Iranian patients with multiple sclerosis. Iran J Neurol. 2013;12(1):32-4.