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Why it's used

Cepodem Suspension is used to treat certain mild to moderate bacterial infections. These include middle ear, throat, skin infections, anus and rectum infections in the women, urinary tract infections, community-acquired pneumonia, sexually transmitted bacterial infection of the urethra and cervix. Cepodem is also used to treat inflammation of the sinuses (acute maxillary sinusitis). It is also used to treat lower respiratory tract infections such as long-term inflammation of the lungs (also called, long-term bronchitis). This medicine works by preventing the formation of an outer layer of the bacteria. This medicine helps by killing the bacteria and removing a bacterial infection from the body.
When not to use
Cepodem Suspension will not work to treat throat infection caused by bacteria (Neisseria gonorrhoeae). Cepodem will not work to treat infections caused by viruses (for example, common cold).
Cephalosporin Antibacterials
Cepodem is a prescription medicine that belongs to a class of medicines called Cephalosporin Antibacterials. Cephalosporins are antibacterial medicines that kill bacteria by interfering with how bacteria build their cell walls.

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How to use

Read the medicine guide provided by your pharmacist, your doctor, or the medicine company. If you have any questions related to Cepodem, ask your doctor or pharmacist. Use Cepodem Suspension as per the instructions provided by your doctor.
Cepodem is consumed with or without food. Cepodem tablets should be taken orally with food to enhance absorption. Cepodem oral suspension may be taken without any regard to the food.

Typical Dosage

The typical dose of Cepodem for adults is 100-400 mg every 12 hours for 5 to 14 days. The usual dose for children is 5 mg/kg/dose (2.3 mg/lb/dose) every 12 hours for 5 to 10 days (maximum 100-200 mg/dose). This medicine is generally used for a period of 5-10 days for throat infections, 14 days for community-acquired pneumonia, 7 days for urinary tract infection, 7-14 days for skin infections, and 10 days for inflammation of the sinuses. This medicine is not known to be addictive or habit-forming.
This medicine should be used on an as-needed basis. Cepodem should be used as directed by the doctor even if you feel well, or even if you think that there is no need for you to use your medicine.
If using the liquid form of this medicine, measure the dose using the provided measuring cup, spoon, or dropper. Before pouring the medicine into the measuring device, you should check the measurement markings carefully. Then, pour the dose amount into the device. After use, clean and store the measuring device in a safe place for your next use. You should not use a tablespoon or teaspoon as the dose measuring devices since it can result in an incorrect dose. If indicated on the product package, shake the medicine before use.

Talk to Your Doctor

Discuss with your doctor if you develop new symptoms. Discuss with your doctor if diarrhea, bloody stool, stomach cramp, and fever. If you have any kidney disease, the dosing interval should be increased to 24 hours. In patients maintained on artificial blood purifying technique (hemodialysis), the dosing should be three times per week after hemodialysis. Consult with your doctor before stopping the use of Cepodem.

Use in Children

If you are giving Cepodem Suspension to a child, be sure to use a product that is for use in children. Use the child's weight or age to find the right dose from the product package or medicine label. You can also read the dosage section of this page to know the correct dose for your child. Else, consult with your doctor and follow their recommendation.

Lab Tests

Your doctor may request that specific lab tests be performed before you start using Cepodem Suspension. Your doctor may ask you to undergo Antibiotic Susceptibility test. This test should be performed to determine organisms susceptibility and treatment suitability.
Medicines may be recommended for uses other than those listed in the medicine guide. You should not use Cepodem Suspension for conditions or symptoms for which it was not prescribed. Do not give Cepodem Suspension to other people, even if they have the same conditions or symptoms that you have. The use of this medicine without the advice of a doctor may cause harm.

Storage

Follow storage instructions on the product package if available. Store Cepodem Suspension controlled room temperature 20° to 25°C (68° to 77°F) for tablet. The suspension should be stored in a freezer at 2° to 8°C (36° to 46°F) after its preparation., and away from moisture. Store this medicine away from children and pets.

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How to take Cepodem

Your dose and how often you take Cepodem will depend on the following factors:
  • age
  • weight
  • patient's health
  • the health of the patient's liver
  • medicines recommended by the doctor
  • any other medicines being used

Cepodem Dosage

Dosage for throat infection

Adult (children and adults aged 12 years and older)
  • Recommended: 100 mg every 12 hours for 5 to 10 days for tablets and granules for oral suspension (200 mg daily)
Children (2 months to 12 years)
  • Recommended: 5 mg/kg/dose (2.3 mg/lb/dose) every 12 hours for 5 to 10 days (granules for oral suspension)
  • Maximum: 100 mg/dose
Children (infants and children aged 1 month - 11 years and body weight 5 kg (11.02lb))
  • Recommended: 20 mg/2.5 ml (half teaspoon) twice daily of 40 mg/5 ml granules for oral suspension
Children (infants and children aged 1 month - 11 years and body weight 10 kg (22.04lb))
  • Recommended: 40 mg/5 ml (full teaspoon) twice daily of 40 mg/5 ml granules for suspension
Children (infants and children aged 1 month - 11 years and body weight 15 kg (33.1 lb))
  • Recommended: 60 mg/7.5 ml (half tablespoon) twice daily of 40 mg/5 ml granules for suspension
Children (infants and children aged 1 month - 11 years and body weight 20 kg (44.1 lb))
  • Recommended: 80 mg/10 ml (2 teaspoons) twice daily of 40 mg/5 ml granules for suspension
Children (infants and children aged 1 month - 11 years and body weight 25 kg (55.12 lb))
  • Recommended: 100 mg/12.5 ml (two and a half teaspoon) twice daily of 40 mg/5 ml granules for suspension

Dosage for acute community-acquired pneumonia

Adult (children and adults aged 12 years and older)
  • Recommended: 200 mg every 12 hours for 14 days for tablets and granules for oral suspension (400 mg daily)

Dosage for long-term inflammation of the lungs (long-terms bronchitis)

Adult (children and adults aged 12 years and older)
  • Recommended: 200 mg every 12 hours for 10 days for tablets (400 mg daily)

Dosage for uncomplicated gonorrhea

Adult (children and adults aged 12 years and older)
  • Recommended: 200 mg once daily for tablets and granules for oral suspension

Dosage for skin and skin structure infection

Adult (children and adults aged 12 years and older)
  • Recommended: 400 mg every 12 hours for 7 to 14 days for tablets and granules for oral suspension (800 mg daily)

Dosage for the sinus infection

Adult (children and adults aged 12 years and older)
  • Recommended: 200 mg every 12 hours for 10 days for tablets and granules for oral suspension (400 mg daily)
Children (2 months to 12 years)
  • Recommended: 5 mg/kg (2.3 mg/lb) every 12 hours for 10 days granules for oral suspension
  • Maximum: 200 mg/dose

Dosage for urinary tract infection

Adult (children and adults aged 12 years and older)
  • Recommended: 100 mg every 12 hours for 7 days for tablets and granules for oral suspension (200 mg daily)

Dosage for the middle ear infection

Children (2 months to 12 years)
  • Recommended: 5 mg/kg (2.3 mg/lb) every 12 hours for 5 days granules for oral suspension
  • Maximum: 200 mg/dose

Dosage for rectal infection in women

Adult (children and adults aged 12 years and older)
  • Recommended: 200 mg once daily for tablets and granules for oral suspension

Minimum Age

1 month

Dosage calculation for children

To calculate the dosage for children please use the weight based dose calculator to calculate the appropriate dosage as per the weight of your child.

Forms

Tablet
Strength: 100 mg, 200 mg
Granules for oral suspension (50 mg/5 ml and 100 mg/5 ml)
Strength: 100 ml, 75 ml, 50 ml

Special Instructions

Patients with kidney dysfunction
This medicine does not require dose modification in patients with creatinine clearance more than 40ml/min. The dosing intervals should be increased to four times in 24 hours if the creatinine clearance is less than 30 ml/min. If the patient is maintained on artificial blood purifying technique called hemodialysis, then the dosing interval should be three times per week after therapy. If the creatinine clearance is less than 10 ml/min., a single dose should be given in every 48 hours.
50 ml oral suspension (50 mg/5 ml)
Shake the bottle to release the granules. Then add water in two equal portions, with vigrous shaking after adding each fraction of water. A total of 29 ml of purified water is used to prepare the oral suspension.
75 ml oral suspension (50 mg/5 ml)
Shake the bottle to release the granules. Then add water in two equal portions, with vigrous shaking after adding each fraction of water. A total of 44 ml of purified water is used to prepare the oral suspension.
100 ml oral suspension (50 mg/5 ml)
Shake the bottle to release the granules. Then add water in two equal portions, with vigrous shaking after adding each fraction of water. A total of 58 ml of purified water is used to prepare the oral suspension.
50 ml oral suspension (100 mg/5 ml)
Shake the bottle to release the granules. Then add water in two equal portions, with vigrous shaking after adding each fraction of water. A total of 29 ml of purified water is used to prepare the oral suspension.
75 ml oral suspension (100 mg/5 ml)
Shake the bottle to release the granules. Then add water in two equal portions, with vigrous shaking after adding each fraction of water. A total of 43 ml of purified water is used to prepare the oral suspension.
100 ml oral suspension (100 mg/5 ml)
Shake the bottle to release the granules. Then add water in two equal portions, with vigrous shaking after adding each fraction of water. A total of 57 ml of purified water is used to prepare the oral suspension.

Missed Dose

The missed dose of Cepodem should be taken immediately when you remember it, skip the dose if its almost time for the next dose. Then continue with the regular schedule. Do not take a double dose to make up the missed dose.

Overdose

What to do if you overdose on Cepodem?
If this happens, the supportive measures and treatment for symptoms should be provided. The artificial blood purifying techniques should be used to remove the excessive level of Cepodem from the body.
Symptoms of an overdose of Cepodem
If you use too much of this medicine, it could lead to dangerous levels of the medicine in your body. In such cases, symptoms of an overdose may include:
If you think you have overdosed on Cepodem Suspension, call a poison control center immediately. You can look up the poison control center information from the Poison Center Finder at TabletWise.com.

Precautions while using Cepodem

Before you use Cepodem, tell your doctor of your medical and health history including the following:
  • cephalosporin allergy
  • colitis
  • penicillin allergy
  • stomach and intestinal diseases
Before you use Cepodem Suspension, discuss with your doctor if you are allergic to it or its ingredients. Your doctor may prescribe an alternative medicine and update your medical records to record this information. Tell your doctor if you are allergic any of the following substances: cephalosporin, or penicillin.
The use of this medicine may change hemoglobin and hematocrit level. The hemoglobin and hematocrit level decreases in patients while using this medicine.
The use of this medicine may change blood cell count. The blood cell count changes (such as eosinophilia, leukocytosis, lymphocytosis, granulocytosis, basophilia, monocytosis, thrombocytosis, leukopenia, neutropenia, lymphocytopenia, low levels of thrombocytes, thrombocythemia) in the patients while using this medicine.
The use of Cepodem Suspension may change bilirubin. This medicine may temporarily increase the level of bilirubin in the patients.
The use of this medicine may change Liver enzyme level. This medicine may temporarily increase the level of liver enzymes (aspartate transaminase, alanine transaminase, gamma-glutamyl transferase, alkaline phosphatase, lactic acid dehydrogenase in the patients.
The use of Cepodem Suspension may change blood glucose level. The blood glucose level changes in patients while using this medicine.

Seizures

Cepodem Suspension can make you feel sleepy. Be careful when using any machinery, driving a vehicle, or doing any other activity that needs you to be fully alert. The consumption of alcohol with Cepodem Suspension can worsen the sleepiness. Cepodem Suspension may cause rarely seizures in some people. If you perform any activities where a loss of consciousness may cause harm to you (or others), you should discuss with your doctor.

Use in Pregnancy

The use of Cepodem during pregnancy should only be when required. No adequate and well-controlled studies of Cepodem have been done in pregnant women.

Use while Breastfeeding

Consult with your doctor on the use of Cepodem Suspension during breastfeeding. This medicine is excreted in human milk. Due to the possibility of serious reactions in babies, a decision should be made whether to discontinue breastfeeding or medicine, taking into account the importance of the drug to the mother.

Use while Conceiving

Consult with your doctor on the use of Cepodem, if you are trying to conceive.

Long-term Use

The long term use of Cepodem may cause overgrowth of bacteria (non-susceptible organisms).

What precautions should be taken during Pregnancy and Nursing, and administering Cepodem to Children or the Older Adults?

Pregnant Women

Only When Necessary
Warning: No adequate and well-controlled studies of Cepodem have been done in pregnant women.

Breastfeeding

Only When Necessary
Warning: There is an increased possibility of serious reactions in babies. A decision should be made whether to discontinue breastfeeding or medicine, taking into account the importance of the drug to the mother.

Younger Adults Population

Possibly safe
Warning: The safety and effectiveness in newborns less than 2 months of age have not been proved.

Older Adults Population

Possibly safe
Warning: 

Cepodem Side-effects

The following side-effects may commonly occur when using Cepodem Suspension. If any of these side-effects worsen or last for a long time, you should consult with your doctor:
  • diarrhea
  • fungal skin rash
  • gas formation
  • headache
  • loss of appetite
  • nausea
  • pressure build up in the stomach
  • stomach pain
  • vaginal infections
  • vomiting
The following side-effects may commonly occur in children when using Cepodem Suspension. Discuss with your doctor if any of these side-effects last for a long time or are severe:
Rarely, the use of Cepodem Suspension may cause the following side-effects:
  • abnormal bleeding from the uterus
  • abnormal microbiological tests
  • abnormal sweating (diaphoresis)
  • accumulation of gas in the stomach
  • acne
  • back pain
  • bacterial infections
  • belching
  • burning or prickling sensation
  • change in dreams
  • chest pain
  • chills
  • collection of pus (abscess)
  • cough
  • difficult urination
  • disturbed focus
  • dizziness
  • dry mouth
  • dry skin
  • dry throat
  • dry, itchy, and irritated skin arround the eyes (eyelid dermatitis)
  • excessive abnormal body movements
  • excessive urination at night
  • eye irritation
  • facial swelling
  • false positive blood test (direct Coombs’ test)
  • fatigue
  • feeling of discomfort
  • generalized pain
  • hair loss
  • hives
  • increase in the number of white blood cells
  • increase in weight
  • increased level of liver enzymes
  • indigestion
  • insomnia
  • itching of the skin
  • lack of energy
  • localized pain
  • localized swelling
  • mouth ulcers
  • multiplication of bacteria
  • need to urinate many times
  • nervousness
  • nightmares
  • oral lesions
  • oral yeast infection
  • pain in muscles
  • palpitation
  • parasitic infections
  • presence of protein in the urine in abnormal quantity
  • prolonged blood clotting time
  • ringing in the ears
  • shakiness
  • skin peeling
  • spinning sensation (vertigo)
  • stuffy nose
  • sunburn
  • taste alterations
  • temporary loss of consciousness
  • tooth pain
  • vaginal pain
  • yeast infection
The following severe side-effects may also occur when using Cepodem Suspension:
Your doctor has prescribed this medicine because they judge that the benefit is greater than the risk posed by side-effects. Many people using this medicine do not have serious cases of side-effects. This page does not contain a complete list of all possible side-effects.
If you experience side-effects or notice other side-effects not listed above, contact your doctor for medical advice. You may also report side-effects to your local food and drug administration authority. You can look up the drug authority contact information from the Drug Authority Finder at TabletWise.com.

Side-effects and Allergic Reactions of Cepodem by Severity and Frequency

Common Side-effects

Following are the common side-effects of this medicine:

Infrequent and Rare Side-effects

Following are the infrequent and rare side-effects of this medicine:

Severe Side-effects

Following are the severe side-effects of this medicine:

Side-effects in Children

Following are the side-effects of this medicine in young patients:

Mild Allergic Reactions

Following are the symptoms of mild allergic reactions to this medicine:

Serious Allergic Reactions

Following are the symptoms of serious allergic reactions to this medicine:
  • rash
  • shock caused by a severe allergic reaction
If an allergic reaction occurs, discontinue taking this medicine. In serious allergic reactions, treatment with epinephrine and other measures like oxygen, intravenous fluids, intravenous antihistamine, and airway management should be given.
If you experience side-effects or notice other side-effects not listed above, contact your doctor for medical advice. You may also report side-effects to your local food and drug administration authority. You can look up the drug authority contact information from the Drug Authority Finder at TabletWise.com.

Warnings

Medicines that prevent Peristalsis

The medicines that hinders the movement of intestine (peristalsis) should not be given to the patients using this medicine.

Overgrowth of the Bacteria

The overgrowth of certain bacteria (Candida and Clostridium difficile) may occur in patients using this medicine. If this occurs, interruption of treatment may required.

Patients using Nephrotoxic Drugs

The patients using nephrotoxic drugs such as aminoglycosides and potential diuretics are at an increased risk. The changes in the functioning of kidneys have been observed with cephalosporin antibiotics, particularly when given in combination with nephrotoxic drugs. The functioning of kidneys should be monitored in such patients.

Anemia, Positive Coomb's Test and Cross-reactions

The cephalosporins may be absorbed on the red blood cells and react with antibodies that act against the Cepodem. Thus there is a risk that a disease in which red blood cells are destroyed (called as, hemolytic anemia), a false positive blood test (Coomb's test) and cross-reactivity with penicillin may occur in patients using this medicine.

Decreased White Blood Cells

The patients using beta-lactam antibiotics are at an increased risk of decreased white blood cells (neutropenia and more rarely deficiency of granulocytes in the blood). If the treatment lasts longer than 10 days, the blood count should be monitored and treatment should be discontinued if white blood cells decreased.

History of Stomach and Intestinal Diseases

This medicine should always be given with caution in patients with a history of stomach and intestinal diseases, particularly colitis.

Inflammation of the Colon

In patients using this medicine, mild to severe inflammation of the colon (antibacterial agent-associated colitis and pseudo-membranous colitis) may occur and can be possibly fatal. If diarrhea occurs during or after taking this medicine, the patients must be diagnosed for colitis. Discontinue the medicine and appropriate treatment should be given to such patients.

Severe Kidney Disease

A decrease in the dose may be required in such patients depending on the functioning of their kidneys.

Pneumonia

Pneumonia caused by Legionella, Mycoplasma and Chlamydia, Staphylococcal pneumoniae are at an increased risk when using this medicine. This medicine is not recommended for the treatment of pneumonia in such patients.

Interactions with Cepodem

When two or more medicines are taken together, it can change how the medicines work and increase the risk of side-effects. In medical terms, this is called as a Drug Interaction.
This page does not contain all the possible interactions of Cepodem Suspension. Share a list of all medicines that you use with your doctor and pharmacist. Do not start, stop, or change the dose of any medicines without the approval of your doctor.

Nephrotoxic Drugs

Cepodem Suspension interacts with Nephrotoxic Drugs, which causes kidney damage in patients. The functioning of kidneys should be closely monitored while using these medicines together.

Oral Anticholinergics

There may be an interaction of Cepodem with Oral Anticholinergics, which are used to block an action of a natural chemical acetylcholine. Using this medicine with oral anticholinergics such as propantheline, decrease the levels of Cepodem in the blood.

Antacids

Cepodem Suspension may interact with Antacids, which are used to neutralize acid in the stomach. Antacids such as sodium bicarbonate, aluminum hydroxide reduce the extent of absorption of this medicine, making it less effective. Antacids should be taken 2 to 3 hours after consuming Cepodem.

Histamine Antagonists

Your doctor's guidelines may need to be followed while taking this medicine along with Histamine Antagonists, which are used to decrease acid production in the stomach. Using this medicine with histamine antagonists such as ranitidine, reduce the level of Cepodem in the blood. Histamine antagonists should be taken 2 to 3 hours after consuming Cepodem.

Antigout Agents

Special instructions need to be followed while taking this medicine along with Antigout Agent such as probenecid, which is used for the treatment of gout. Using this medicine with probenecid increases the level of Cepodem in the blood.

Genetic Diseases

Your doctor's guidelines may need to be followed while taking this medicine along with Genetic Diseases. This medicine should not be taken in patients with genetic diseases (such as decreased absorption of glucose-galactose, galactose intolerance or the Lapp lactase deficiency).

Fehling's or Benedict's Solutions

Special instructions need to be followed while taking this medicine along with Fehling's or Benedict's solutions or with copper sulphate test tablets, which are used for glucose test in the urine. This medicine gives a false positive reaction with Benedict's or Fehling's solutions or with copper sulfate test tablets used for the detection of glucose in the urine. But no such false positive reaction was seen with tests based on enzymatic glucose oxidase reactions.

Coomb's Test

Cepodem Suspension interacts with Coomb's test, that is a blood test performed in pregnant women or in patients before blood transfusion. The cephalosporins, including Cepodem, are known to induce a false positive direct Coombs’ test occasionally.

Oestrogens

There may be an interaction of Cepodem with Oestrogens, which are used in hormonal therapy. The contraceptive effect of oestrogens is reduced when used simultaneously with this medicine.

Anticoagulant

Cepodem Suspension may interact with Anticoagulant, which helps by preventing formation of blood clots. Using this medicine with anticoagulants such as warfarin and coumarins together may increase the effect of anticoagulants. The monitoring of increased ratio of the blood clotting time to a control sample in blood is recommended in patients taking Cepodem with anticoagulants.

Sunset Yellow (E110)

Cepodem Suspension may interact with Sunset Yellow (E110), which is used as food dye. The use of sunset yellow with Cepodem may cause allergic reactions.

Interactions of Cepodem by Severity

Moderate

The following medicines may interact when taken together and can increase your risk of harmful effects. Please consult with your doctor or pharmacist before taking these medicines together.

When should Cepodem be not used?

Severe Allergic Reaction

This medicine should not be used in patients who are allergic to Cepodem, or any other cephalosporins or to any of the component.

History of Severe Allergic Reaction (anaphylaxis)

This medicine should not be used in patients with the previous history of severe or immediate allergic reactions (anaphylaxis) to penicillin or any other beta-lactam antibiotic.

Traveling With Medication

  • Ensure that you carry enough doses of each of your prescription medicines to last the entire trip. The best place to store your medicines is in the carry on baggage. However, while flying, if carrying liquid medicines, make sure you do not go over the limits imposed for carry-on liquids.
  • While traveling overseas, make sure that you can carry each of your prescription medicines legally to your destination country. One way to ensure this is by checking with your destination country's embassy or website.
  • Make sure that you carry each of your medicines in their original packaging, which should typically include your name and address, and the details of the prescribing doctor.
  • If your travel involves crossing time zones, and you are required to take your medicine as per a fixed schedule, make sure that you adjust for the change in time.

Expired Medication

Taking a single dose of expired Cepodem is unlikely to cause a side-effect. However, please discuss with your doctor or pharmacist, if you feel unwell or sick. An expired medicine may become ineffective in treating your prescribed conditions. To be on the safe side, it is important not to use an expired drug. You are much safer by always keeping a fresh supply of unexpired medicines.

Safe Disposal of Medication

  • If there are disposal instructions on the package, please follow the instructions.
  • If there are medicine take-back programs in your country, you should contact the respective authority to arrange for the disposal of the medicine. For example, in the USA, the Drug Enforcement Administration regularly hosts National Prescription Drug Take-Back events.
  • If there are no take-back programs, mix the medicine with dirt and place them in a sealed plastic bag. Throw the plastic bag in your household trash. Separately, remove all personal information including the prescription label from the medicine packaging and then dispose off the container.
  • If specifically indicated on the medicine package that it needs to be flushed down the toilet when no longer needed, perform the required step.
This page provides information for Cepodem Suspension .
Bacterial Infections
Ear Infections
Urinary Tract Infections
Pneumonia

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