When two or more
medicines are taken together, it can change how the medicines work and increase the risk of side-effects. In medical terms, this is called as a
Drug Interaction.
This page does not contain all the possible interactions of Amotril tablet. Share a list of all medicines that you use with your doctor and pharmacist. Do not start, stop, or change the dose of any
medicines without the approval of your doctor.
Amotril tablet interacts with anticonvulsants (hydantoins,
phenobarbital,
clonazepam,
carbamazepine,
phenytoin, and
sodium valporate), which are used to treat
epilepsy. When Amotril is used with anticonvulsants, it may cause sedation, lack of interest (apathy), harmful effects, or epilepsy (absence status epilepticus). Also, it may increase the clearance of Amotril by decreasing the level of Amotril. Precaution should be taken and the risk should be kept in mind when using these medicines together.
There may be an interaction of
Amotril with
propantheline, which is used for the treatment of excessive sweating. When
propantheline is used with Amotril, it may decrease the level of Amotril in the body.
Amotril tablet may interact with
ranitidine, which is used to decrease stomach acid. When Amotril is used with
ranitidine, it may alter the activity of Amotril in the body.
Your doctor's guidelines may need to be followed while taking this medicine along with antianxiety, thioxanthene, and butyrophenones, which are used to treat
anxiety, mental or emotional conditions, and
schizophrenia respectively. When Amotril is used with antianxiety, thioxanthene, or butyrophenones,it may increase the calming effect (central nervous system depressant effect) of Amotril on
brain.
Special instructions need to be followed while taking this medicine along with narcotics, non-barbiturate hypnotics, and barbiturates, which are used to treat
pain, sleeplessness, and
anxiety respectively. When Amotril is used with narcotics, non-barbiturate hypnotics, or barbiturates, it may increase the calming effect (central nervous system depressant effect) of Amotril on
brain.
Your doctor's guidelines may need to be followed while taking this medicine along with
rifampicin and
levodopa, which is used to treat
tuberculosis and symptoms of movement disorders (Parkinson-like symptoms) respectively. When Amotril is used with
rifampicin, it may
interfere in the metabolism of Amotril. Also using Amotril with levodopa may decrease the effect of Amotril.
Special instructions need to be followed while taking this medicine along with
cimetidine,
fluvoxamine,
disulfiram, and
ritonavir, which are used to treat
heartburn,
depression, alcoholism, and
human immunodeficiency virus infection respectively. When Amotril is used with cimetidine, fluvoxamine, disulfiram, or ritonavir, it may increase the levels of Amotril in the blood.
Amotril tablet interacts with
amprenavir, which is used in the treatment of
human immunodeficiency virus infection. When Amotril is used with amprenavir, it may increase the risk of slow or ineffective breathing and sedation.
Your doctor's guidelines may need to be followed while taking this medicine along with
nabilone,
tizanidine, and
opioid analgesics, which are used to treat
nausea and vomiting during
cancer treatment, muscle
cramps and
pain respectively. Using Amotril with nabilone, tizanidine, or opioid analgesics may increase the sedative effects of Amotril.
Special instructions need to be followed while taking this medicine along with
mirtazapine and
lofexidine, which are used to treat
depression and withdrawal symptoms caused during stopping
opioids respectively. The sedative effects of Amotril are increased when this medicine is used with
baclofen, mirtazapine, or lofexidine.
Amotril tablet interacts with
antihistamines,
baclofen, and general anesthetics, which are used to treat
allergies, muscle spasms and during
surgery respectively. When Amotril is used with general anesthetics, antihistamines, or baclofen, it may increase the sedative effects of Amotril.
There may be an interaction of
Amotril with antihypertensive drugs (angiotensin-converting
enzyme inhibitors,
beta-blockers, adrenergic neuron blockers,
hydralazine, angiotensin-II receptor antagonists,
calcium channel blockers,
clonidine,
methyldopa,
diazoxide,
diuretics,
minoxidil,
nitrates or
nitroprusside) which are used to treat high blood pressure. When Amotril is used with antihypertensive drugs, it may increase the blood pressure lowering effect of these medicines.
Amotril tablet may interact with
moxonidine or
alpha-blockers, which are used to treat high blood pressure. When Amotril is used with alpha-blockers or moxonidine, it may increase the blood pressure lowering and sedative effects.
Amotril tablet may interact with central nervous system depressants. When Amotril is used with central nervous system depressants, it may increase the risk of severe sedation, slow and ineffective breathing and worsen of heart disease. Patients should not use both medicines together.