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High doses of prenatal vitamin D not associated with children’s asthma risk

Wednesday, March 13, 2019 -- Women who took high doses of vitamin D supplementation during pregnancy did not impact their child’s risk for asthma by the age of 6 years, according to data recently published in JAMA.“The Copenhagen Prospective Studies on Asthma in Childhood 2010 vitamin D randomized clinical trial found that at the age of 3 years, children of women randomized to high-dose vs. standard-dose vitamin D did not have a statistically significant reduced risk of persistent wheeze; however, a clinically important protective effect could not be excluded,” Niklas Brustad, MD, of the Copenhagen

Unreasonable prescription costs leading to life-threatening asthma attacks

Tuesday, February 26, 2019 -- Asthma UK has revealed that people with asthma are rationing their medication due to prescription costs.

Asthma More Common in Opioid-Dependent Patients

Sunday, February 24, 2019 -- (MedPage Today) -- Also, women taking opioids have greatest asthma risk

Study finds new genetic clues associated with asthma in African ancestry populations

Thursday, February 21, 2019 -- In the largest study of its kind, researchers at the University of Colorado Anschutz Medical Campus have found new clues into the parts of the human genome associated with the higher rates of asthma in those of African ancestry.

Asthma classes in school may help reduce attacks

Friday, February 15, 2019 -- (Reuters Health) - School-age children with asthma who receive education on managing the condition may have fewer attacks, emergency room visits and hospitalizations than those who don't get such classes, a recent study suggests.

New asthma pill to target airway muscles

Friday, February 15, 2019 -- Researchers are developing a new asthma pill Fevipiprant to target airway muscles to decrease attacks, potentially offering the first new oral treatment for asthma in 20 years.

New eHealth tool shows potential to improve quality of asthma care

Thursday, February 14, 2019 -- A new electronic decision support tool for managing asthma has the potential to improve the quality of asthma care in primary care settings, suggests a study led by St. Michael's Hospital in Toronto, Canada.

Breast pumps could be transmitting asthma-causing bacteria in babies, finds study

Thursday, February 14, 2019 -- Mothers across the world use breast pumps to pump put the milk that is fed to their babies. A new study has revealed that these pumps may not be safe and may be contaminated with bacteria that can cause asthma in the babies later in life. The results of this study were published in the latest issue of the journal Cell Host & Microbe.

[Research Articles] DP2 antagonism reduces airway smooth muscle mass in asthma by decreasing eosinophilia and myofibroblast recruitment

Wednesday, February 13, 2019 -- Increased airway smooth muscle mass, a feature of airway remodeling in asthma, is the strongest predictor of airflow limitation and contributes to asthma-associated morbidity and mortality. No current drug therapy for asthma is known to affect airway smooth muscle mass. Although there is increasing evidence that prostaglandin D2 type 2 receptor (DP2) is expressed in airway structural and inflammatory cells, few studies have addressed the expression and function of DP2 in airway smooth muscle cells. We report that the DP2 antagonist fevipiprant reduced airway smooth muscle mass in bronchial biopsies from patients with asthma who had participated in a previous randomized placebo-controlled trial. We developed a computational model to capture airway remodeling. Our model predicted that a reduction in

Should Hospitalized Asthma Patients Receive Antibiotics?

Monday, February 04, 2019 -- Our findings support the current guidelines that antibiotics are not indicated in patients with asthma; Continue reading → The post Should Hospitalized Asthma Patients Receive Antibiotics? appeared first on

Acceptance and Commitment Therapy for Parental Management of Childhood Asthma: An RCT

Friday, February 01, 2019 -- BACKGROUND: Few trials have been conducted to address the psychological difficulties of parents in managing their child’s asthma. Fostering parental psychological flexibility through Acceptance and Commitment Therapy (ACT) may help parents to accept these psychological difficulties and improve their management of childhood asthma. METHODS: In this randomized controlled trial, a 4-session, group-based ACT plus asthma education (ACT group) was compared with an asthma education talk plus 3 telephone follow-ups (control group) to train parents of children diagnosed with asthma. The use of health care services due to asthma exacerbations in children and the psychological well-being of their parents were assessed before, immediately after, and at 6 months after the intervention. RESULTS: A total of 168 parents and their children

A meta-analysis of anti-interleukin-13 monoclonal antibodies for uncontrolled asthma

Thursday, January 31, 2019 -- by Hang Li, Kai Wang, Huiting Huang, Wenbin Cheng, Xiaohong Liu More and more clinical trials have tried to assess the clinical benefit of anti-interleukin (IL)-13 monoclonal antibodies for uncontrolled asthma. The aim of this study is to evaluate the efficacy and safety of anti-IL-13 monoclonal antibodies for uncontrolled asthma. Major databases were searched for randomized controlled trials comparing the anti-IL-13 treatment and a placebo in uncontrolled asthma. Outcomes, including asthma exacerbation rate, forced expiratory volume in 1 second (FEV1), Asthma Quality of Life Questionnaire (AQLQ) scores, rescue medication use, and adverse events were extracted from included studies for systematic review and meta-analysis. Five studies involving 3476 patients and two anti-IL-13 antibodies (lebrikizumab and tralokinumab) were included in this

FDA approves first generic Advair Diskus for asthma, COPD

Thursday, January 31, 2019 -- The FDA recently issued approval to the first generic version of GlaxoSmithKline’s Advair Diskus (fluticasone propionate and salmeterol inhalation powder) for reducing exacerbations and airflow obstruction in patients aged 4 years and older with asthma or COPD, according to a press release by the agency.“Today’s approval of the first generic drug product for one of the most commonly prescribed asthma and COPD inhalers in the U.S. is part of our longstanding commitment to advance access to lower cost, high quality generic alternatives,” Janet Woodcock, MD, director of

FDA approves Mylan's generic of Advair asthma treatment

Wednesday, January 30, 2019 -- The U.S. Food and Drug Administration (FDA) approved Mylan NV's generic version of GlaxoSmithKline-developed blockbuster asthma treatment Advair, driving shares of Mylan 7 percent higher on Wednesday.

Pediatric corticosteroid use increases with poor asthma control documentation

Tuesday, January 29, 2019 -- Children with uncontrolled or undocumented control of their asthma symptoms were more likely to receive prescriptions for both oral and inhaled corticosteroids, according to research published in Clinical Pediatrics.“Out of all the recommendations in the NIH asthma guidelines, making sure physicians document asthma control or asthma severity is a crucial recommendation,” Michael Cabana, MD, MPH, professor of pediatrics, epidemiology and biostatistics at the University of California, San Francisco, told Infectious Diseases in Children. “This information helps form the basis

Antibiotics Lead to Longer Hospital Stays for Asthma

Monday, January 28, 2019 -- (MedPage Today) -- Costs were higher too, retrospective study found

Fish Oil Flops for Asthma Control in Overweight Youth

Friday, January 25, 2019 -- (MedPage Today) -- No benefit versus soybean oil in exacerbations or lung function

Pediatric Asthma Care Management Program Extends to 7K Schools Nationwide

Monday, January 21, 2019 -- Rajiv Leventhal, Managing EditorA regionally-established pediatric asthma care management program, which includes leveraging a student health record platform, is extending its reach.

This Japanese herbal medicine reduces asthma in patients with upper airway disease

Monday, January 21, 2019 -- (Natural News) Research has found that traditional medicine could hold the key to managing asthma, especially in patients with upper airway disease. In a study published in The Journal of Alternative and Complementary Medicine, a team of scientists from Japan revealed that Shin’iseihaito, a herbal medicine traditionally used in Japanese medicine, can potentially reduce the incidence... Read More

Effect of Mometasone Furoate and Formoterol on Risk of Serious Asthma Outcomes

Wednesday, January 16, 2019 -- The combined use of mometasone furoate and formoterol in adults and adolescents with persistent asthma may not increase asthma-related adverse events and may reduce the risk of worsening asthma outcomes.

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