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    Brain Tumors

    Health    Brain Tumors

    A brain tumor is a growth of abnormal cells in the tissues of the brain. Brain tumors can be benign, with no cancer cells, or malignant, with cancer cells that grow quickly. Some are primary brain tumors, which start in the brain. Others are metastatic, and they start somewhere else in the body and move to the brain.

    Brain tumors can cause many symptoms. Some of the most common are

    • Headaches, often in the morning
    • Nausea and vomiting
    • Changes in your ability to talk, hear, or see
    • Problems with balance or walking
    • Problems with thinking or memory
    • Feeling weak or sleepy
    • Changes in your mood or behavior
    • Seizures

    Doctors diagnose brain tumors by doing a neurologic exam and tests including an MRI, CT scan, and biopsy. Treatment options include watchful waiting, surgery, radiation therapy, chemotherapy, and targeted therapy. Targeted therapy uses substances that attack cancer cells without harming normal cells. Many people get a combination of treatments.

    NIH: National Cancer Institute

    Symptoms of Brain Tumors

    The following features are indicative of Brain Tumors:
    • headache
    • seizures
    • problems with vision
    • vomiting
    • mental changes
    • difficulty in walking
    • difficulty in writing
    References: 1

    Common Causes of Brain Tumors

    The following are the most common causes of Brain Tumors:
    • exposure to vinyl chloride
    • exposure to ionizing radiation
    • genetic mutations or deletions of tumor suppressor genes
    • Von Hippel–Lindau disease
    • multiple endocrine neoplasia
    References: 1

    Other Causes of Brain Tumors

    The following are the less common causes of Brain Tumors:
    • neurofibromatosis type 2
    References: 1

    Risk Factors of Brain Tumors

    The following factors may increase the likelihood of Brain Tumors:
    • neurofibromatosis
    • exposure to vinyl chloride
    • Epstein–Barr virus infection
    • ionizing radiations

    Prevention of Brain Tumors

    Yes, it may be possible to prevent Brain Tumors.

    Occurrence of Brain Tumors.

    Degree of Occurrence

    The following are number of Brain Tumors cases seen each year worldwide:
    • Rare between 10K - 50K cases

    Common Age Group

    Brain Tumors most commonly occurs in the following age group:
    • Can happen at any age

    Common Gender

    Brain Tumors most commonly occurs in the following gender:
    • Not gender specific
    References: 1

    Lab Tests and Procedures for Diagnosis of Brain Tumors

    The following lab tests and procedures are used to detect Brain Tumors:
    • MRI scan: To diagnose brain tumors
    • Neurological Exam: To check the vision, hearing, balance, coordination, strength and reflexes
    References: 2, 3

    Doctor for Diagnosis of Brain Tumors:

    Patients should visit the following specialists if they have symptoms of Brain Tumors:
    • Neurologist

    Complications of Brain Tumors if Untreated

    Yes, Brain Tumors causes complications if it is not treated. Below is the list of complications and problems that may arise if Brain Tumors is left untreated:
    • cerebral hernia
    References: 4

    Procedures for Treatment of Brain Tumors

    The following procedures are used to treat Brain Tumors:
    • Surgery: Remove the brain tumours
    • Radiation Therapy: Kills tumour cells by emission of radiations
    • Chemotherapy: To kill tumor cells
    • Targeted drug therapy: Blocks the abnormalities and can kill the cancer cells
    References: 5

    Self-care for Brain Tumors

    The following self-care actions or lifestyle changes may help in the treatment or management of Brain Tumors:
    • Hire tutor for school-age children: Cope with changes in their memory and thinking after a brain tumor
    References: 5

    Alternative Medicine for Treatment of Brain Tumors

    The following alternate medicine and therapies are known to help in the treatment or management of Brain Tumors:
    • Physical therapy: Improves motor skills and coordination and treats orthopedic abnormalities
    • Speech therapy: Improves speaking and eating abilities
    • Occupational therapy: Improves the functional abilities
    References: 5

    Time for Treatment of Brain Tumors

    While time-period of treatment for each patient may vary, below is the typical time-period for Brain Tumors to resolve if treated properly under an expert supervision:
    • Disease cannot be treated but only maintained or effects reduced
    References: 6

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    Questions - Brain Tumors

    Brain cancer can run in families. Both behavioral and biological factors impact one’s risk. Inherited genes cannot be controlled. However, one can control their behavior and may decrease their risk this way. Smoking, alcohol consumption, chemical exposure, and radiation exposure should all be avoided to decrease one’s risk.
    1. Reilly KM. Brain tumor susceptibility: the role of genetic factors and uses of mouse models to unravel risk. Brain Patho 2009; 19: 121-131. URL: Accessed May 20, 2018.
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    News, Updates and Latest Articles - Brain Tumors

    Latest news and updates related to Brain Tumors. Subscribe to get latest posts via email or subscribe to a RSS feed.

    Scientists explore ways for drug therapies to reach deadly brain tumors

    Wednesday, August 15, 2018 -- The blood-brain barrier is a specialized network of vascular and brain cells that acts as the brain's security system, helping to safeguard the brain and regulate the flow of substances into and out of it.

    Added Value of Spectroscopy to Perfusion MRI in the Differential Diagnostic Performance of Common Malignant Brain Tumors [ADULT BRAIN]

    Tuesday, August 14, 2018 -- BACKGROUND AND PURPOSE: Perfusion and spectroscopic MR imaging provide noninvasive physiologic and metabolic characterization of tissues, which can help in differentiating brain tumors. We investigated the diagnostic role of perfusion and spectroscopic MR imaging using individual and combined classifiers of these modalities and assessed the added performance value that spectroscopy can provide to perfusion using optimal combined classifiers that have the highest differential diagnostic performance to discriminate lymphomas, glioblastomas, and metastases. MATERIALS AND METHODS: From January 2013 to January 2016, fifty-five consecutive patients with histopathologically proved lymphomas, glioblastomas, and metastases were included after undergoing MR imaging. The perfusion parameters (maximum relative CBV, maximum percentage of signal intensity recovery) and spectroscopic concentration ratios (lactate/Cr, Cho/NAA, Cho/Cr, and lipids/Cr) were analyzed

    Preoperative Mapping of the Supplementary Motor Area in Patients with Brain Tumor Using Resting-State fMRI with Seed-Based Analysis [FUNCTIONAL]

    Tuesday, August 14, 2018 -- BACKGROUND AND PURPOSE: The supplementary motor area can be a critical region in the preoperative planning of patients undergoing brain tumor resection because it plays a role in both language and motor function. While primary motor regions have been successfully identified using resting-state fMRI, there is variability in the literature regarding the identification of the supplementary motor area for preoperative planning. The purpose of our study was to compare resting-state fMRI to task-based fMRI for localization of the supplementary motor area in a large cohort of patients with brain tumors presenting for preoperative brain mapping. MATERIALS AND METHODS: Sixty-six patients with brain tumors were evaluated with resting-state fMRI using seed-based analysis of hand and orofacial motor regions. Rates of

    Arterial Spin-Labeling in Children with Brain Tumor: A Meta-Analysis [PEDIATRICS]

    Tuesday, August 14, 2018 -- BACKGROUND: The value of arterial spin-labeling in a pediatric population has not been assessed in a meta-analysis. PURPOSE: Our aim was to assess the diagnostic accuracy of arterial spin-labeling–derived cerebral blood flow to discriminate low- and high-grade tumors. DATA SOURCES: MEDLINE, EMBASE, the Web of Science Core Collection, and the Cochrane Library were used. STUDY SELECTION: Pediatric patients with arterial spin-labeling MR imaging with verified neuropathologic diagnoses were included. DATA ANALYSIS: Relative CBF and absolute CBF and tumor grade were extracted, including sequence-specific information. Mean differences in CBF between low- and high-grade tumors were calculated. Study quality was assessed. DATA SYNTHESIS: Data were aggregated using the bivariate summary receiver operating characteristic curve model. Heterogeneity was explored with meta-regression and

    Duke Team Finds Missing Immune Cells That Could Fight Lethal Brain Tumors

    Monday, August 13, 2018 -- NewsA mysterious lack of T-cells has hindered the immune system's ability to fight glioblastoma.Contributed Author: Duke University Medical CenterTopics: Oncology


    1. Wikipedia Brain tumor - Accessed: February 20, 2017.
    2. Mayo Clinic Brain Tumor - Accessed: February 20, 2017.
    3. Larner AJ. Referral guidelines for suspected central nervous system or brain tumours. J Neurol Neurosurg Psychiatr. 2006;77(12):1305-6. - Accessed: February 20, 2017.
    4. MedlinePlus Brain herniation - Accessed: February 20, 2017.
    5. Mayo Clinic Brain tumor - Accessed: February 20, 2017.
    6. Americal Cancer Society Survival Rates for Selected Adult Brain and Spinal Cord Tumors - Accessed: February 20, 2017.
    7. Source:

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    This page was last updated on 8/08/2018.
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