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Inability of the exocrine pancreas to produce and secrete an adequate amount of digestive enzymes into the small intestine. Patients present with symptoms of malabsorption syndrome, abdominal discomfort, and bloating. Causes include chronic pancreatitis, cystic fibrosis, and autoimmune disorders.

Symptoms of Exocrine Pancreatic Insufficiency

The following features are indicative of Exocrine Pancreatic Insufficiency:
  • weight loss
  • fatigue
  • steatorrhea
  • edema
  • anemia
  • bleeding disorders
  • metabolic bone disease
  • neurologic manifestation
  • hypocalcemia

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Common Causes of Exocrine Pancreatic Insufficiency

The following are the most common causes of Exocrine Pancreatic Insufficiency:
  • chronic pancreatitis
  • cystic fibrosis

Risk Factors for Exocrine Pancreatic Insufficiency

The following factors may increase the likelihood of Exocrine Pancreatic Insufficiency:
  • sepsis
  • diabetes
  • cardiac arrest
  • hyperlactacidemia
  • shock
  • invasive mechanical ventilation
  • haemodialysis

Prevention of Exocrine Pancreatic Insufficiency

Yes, it may be possible to prevent Exocrine Pancreatic Insufficiency. Prevention may be possible by doing the following:
  • stop smoking
  • avoid alcohol consumption
  • dietary consultation

Occurrence of Exocrine Pancreatic Insufficiency

Number of Cases

The following are the number of Exocrine Pancreatic Insufficiency cases seen each year worldwide:
  • Very common > 10 Million cases

Common Age Group

Exocrine Pancreatic Insufficiency can occur at any age.

Common Gender

Exocrine Pancreatic Insufficiency can occur in any gender.

Lab Tests and Procedures for Diagnosis of Exocrine Pancreatic Insufficiency

The following lab tests and procedures are used to detect Exocrine Pancreatic Insufficiency:
  • Fecal elastase test: To determine the disorder of pancreas
  • Fecal fat test: To measure the amount of fat in feces
  • Pancreatic function test: To diagnose pancreas problems

Doctor for Diagnosis of Exocrine Pancreatic Insufficiency

Patients should visit the following specialists if they have symptoms of Exocrine Pancreatic Insufficiency:
  • Gastroenterologist

Complications of Exocrine Pancreatic Insufficiency if untreated

Yes, Exocrine Pancreatic Insufficiency causes complications if it is not treated. Below is the list of complications and problems that may arise if Exocrine Pancreatic Insufficiency is left untreated:
  • malnutrition-related complications
  • cardiovascular events

Procedures for Treatment of Exocrine Pancreatic Insufficiency

The following procedures are used to treat Exocrine Pancreatic Insufficiency:
  • Pancreatic enzyme replacement products: To break down fats, proteins and carbohydrates

Last updated date

This page was last updated on 2/04/2019.
This page provides information for Exocrine Pancreatic Insufficiency.

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