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Lorahist Tablet

Generic Name(s): Loratadine

Why it's used

Lorahist Tablet is used to relieve symptoms of seasonal allergy (seasonal allergic rhinitis) and other upper respiratory tract allergies. This medicine works by restricting the action of a natural chemical (called as, histamine) which acts on the body cell sites (H1 histamine receptor). Lorahist is also used to treat long-term hives.
Antihistamines
Lorahist belongs to a class of medicines called Antihistamines. Antihistamines help in relieving allergic symptoms. They do so by blocking the effects of histamines. Histamines are produced by the body and in-turn cause fever, itching, sneezing, a runny nose, or watery eyes in allergic conditions.

How to use

Read the medicine guide provided by your pharmacist, your doctor, or the medicine company. If you have any questions related to Lorahist, ask your doctor or pharmacist. Use Lorahist Tablet as per the instructions provided by your doctor.
Lorahist is consumed with or without food. Swallow the whole tablet of Lorahist with water.
The typical dose of Lorahist for adults is 10 mg once daily or 2 teaspoonfuls (10 mg) of syrup once daily. The usual dose for children is 5 mg (1 teaspoonful) once daily. The maximum dose for adult patients of Lorahist is 10 mg per day. It takes 1 to 3 hours for this medicine to start its action.
Discuss with your doctor if your condition persists or worsens or if you develop new symptoms. Discuss with your doctor if swelling of the face, swelling of lips, swelling of the tongue, swelling of the throat, difficulty in breathing due to narrowing of the airways, shock, rash, itching, and collapse. If you have any kidney disease, an initial dose of 10 mg every other day is recommended in patients having kidney disease with clearance rate less than 30 ml/min. In children of age 2 to 5 years with kidney disease, the initial dose should be 5 mg per day. If you have issues with the health of your liver, a low initial dose of 10 mg every other day is recommended in adults and children weighing more than 30 kg or 66.1 lb. In children weighing less than 30 kg or 66.1 lb, a dose of 5 ml (5 mg) is recommended.
If you are giving Lorahist Tablet to a child, be sure to use a product that is for use in children. Use the child's weight or age to find the right dose from the product package or medicine label. You can also read the dosage section of this page to know the correct dose for your child. Else, consult with your doctor and follow their recommendation.
If using the orally-disintegrating form of this medicine, make sure you do not consume any food or fluid 5 minutes before or after taking this medicine. Before taking the medicine out of the package, wash your hands thoroughly. Place the medicine on the tongue. Make sure you do not chew or swallow the medicine. You do not need to drink water after consuming the medicine. In certain cases, the medicine can taste slightly bitter. Also, ensure that you do not break or split the medicine.
If using the rapidly-dissolving tablet form of this medicine, chew this medicine or allow the medicine to dissolve on the tongue. Next, swallow the medicine with or without water.
If using the liquid form of this medicine, measure the dose using the provided measuring cup, spoon, or dropper. Before pouring the medicine into the measuring device, you should check the measurement markings carefully. Then, pour the dose amount into the device. After use, clean and store the measuring device in a safe place for your next use. You should not use a tablespoon or teaspoon as the dose measuring devices since it can result in an incorrect dose. If indicated on the product package, shake the medicine before use.
Medicines may be recommended for uses other than those listed in the medicine guide. You should not use Lorahist Tablet for conditions or symptoms for which it was not prescribed. Do not give Lorahist Tablet to other people, even if they have the same conditions or symptoms that you have. The use of this medicine without the advice of a doctor may cause harm.
Follow storage instructions on the product package if available. Store Lorahist Tablet at 2-30°C (36-86°F) for tablet, 2-25°C (36-77°F) for syrup and rapidly dissolving tablet, and 20-25°C (68-77°F) for suspension and capsule, and away from moisture. Store this medicine away from children and pets.

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How to take Lorahist

The dose and frequency of using Lorahist will depend on the following factors:
  • age of the patient
  • the weight of the patient
  • patient's health
  • the health of the patient's liver
  • the health of the patient's kidneys

Lorahist Dosage

Dosage for symptoms of seasonal allergy (seasonal allergic rhinitis) and other upper respiratory tract allergies

Adult (adults)
  • Recommended: 10 mg (2 teaspoonfuls) once daily
  • Maximum: 10 mg (2 teaspoonfuls) daily
Children (aged 6 years and above)
  • Recommended: 10 mg (2 teaspoonfuls) once daily
  • Maximum: 10 mg (2 teaspoonfuls) daily
Children (aged 2 to 5 years)
  • Recommended: 5 mg (1 teaspoonful) once daily
  • Maximum: 5 mg (1 teaspoonful) daily
Children (aged 2-12 years and weighing more than 30 kg or 66.1 lb)
  • Recommended: 10 mg once daily

Dosage for long-term hives

Adult (adults)
  • Recommended: 10 mg (2 teaspoonfuls) once daily
  • Maximum: 10 mg (2 teaspoonfuls) daily
Children (aged 6 years and above)
  • Recommended: 10 mg (2 teaspoonfuls) once daily
  • Maximum: 10 mg (2 teaspoonfuls) daily
Children (aged 2 to 5 years)
  • Recommended: 5 mg (1 teaspoonful) once daily
  • Maximum: 5 mg (1 teaspoonful) daily
Children (aged 2-12 years and weighing more than 30 kg or 66.1 lb)
  • Recommended: 10 mg once daily

Minimum Age

2 year

Dosage calculation for children

To calculate the dosage for children please use the weight based dose calculator to calculate the appropriate dosage as per the weight of your child.

Forms

Tablet
Strength: 10 mg
Syrup
Strength: 1 mg/ml
Tablet, orally disintegrating
Strength: 5 mg and 10 mg
Oral suspension
Strength: 5 mg/5 ml
Capsule
Strength: 10 mg
Tablet, chewable
Strength: 5 mg
Oral solution
Strength: 5 mg/5 ml

Special Instructions

Patients with liver disease
A low initial dose of 10 mg every other day is recommended in adults and children weighing more than 30 kg (66.1 lb). In children weighing less than 30 kg (66.1 lb), a dose of 5 ml (5 mg) is recommended.
Patients with kidney disease
An initial dose of 10 mg every other day is recommended in patients having kidney disease with clearance rate less than 30 ml/min.
Rapidly disintegrating tablets
The Lorahist rapidly disintegrating tablets can be taken with or without water. These tablets should be placed at the tongue. The disintegration of Lorahist occurs immediately.

Missed Dose

If a dose of Lorahist is missed, take it as soon as you remember. Skip the dose, if its almost time for next dose. Do not take a double dose to make up for the missed one.

Overdose

What to do if you overdose on Lorahist?
The treatment for overdose symptoms and supportive measures should be provided as required. Vomiting (emesis) should be induced in patients except in those with altered consciousness. Then, a slurry of charcoal (a carbon, used to absorb poisonous substances from the body) with water should also be given. In case, vomiting is unsuccessful or not recommended, stomach emptying (gastric lavage) can be done using normal saline. The use of saline cathartics may help in rapid passage of bowel content. After this, careful monitoring of the patient is recommended.
Symptoms of an overdose of Lorahist
If you use too much of this medicine, it could lead to dangerous levels of the medicine in your body. In such cases, symptoms of an overdose may include:
  • drowsiness
  • headache
  • increased heartbeat
  • involuntary or uncontrolled movements (extrapyramidal signs)
  • palpitation
If you think you have overdosed on Lorahist Tablet, call a poison control center immediately. You can look up the poison control center information from the Poison Center Finder at TabletWise.com.

Precautions while using Lorahist

Before you use Lorahist Tablet, tell your doctor if you are allergic to it or its ingredients. Your doctor may prescribe an alternative medicine and update your medical records to record this information.
Before you use Lorahist, tell your doctor of your medical history including liver disease, or kidney disease.
Lorahist Tablet should be used in pregnancy only when required. There are no adequate and well-controlled studies of Lorahist has been performed in pregnant women. Lorahist Tablet should be used while breastfeeding only when required. Lorahist may pass into the breast milk. A choice should be made whether to discontinue the breastfeeding or to discontinue using this medicine; this decision depends on the importance of the Lorahist to the mother. Consult with your doctor on the use of Lorahist Tablet, if you are trying to conceive.
Lorahist Tablet can make you feel sleepy. Be careful while driving, using machinery, or doing any other activity that needs you to be alert. The consumption of alcohol with Lorahist Tablet can make you feel more sleepy. Lorahist Tablet may cause seizures in some people. Discuss with your doctor if you perform activities where a loss of consciousness may cause you or others harm.
This medicine may increase your sensitivity to sunlight. If this happens, limit your time outdoors and do not tan to prevent sunburns. Cover your skin when you are outdoors or use a sunscreen. In case you get a sunburn, consult with your doctor.

What precautions should be taken during Pregnancy and Nursing, and administering Lorahist to Children or the Older Adults?

Pregnant Women

Only When Necessary
Warning: There are no adequate and well-controlled studies of Lorahist has been performed in pregnant women.

Breastfeeding

Precaution
Warning: Lorahist may pass into the breast milk.

Younger Adults Population

Possibly safe
Warning: The safety and effectiveness of Lorahist in the children under two years have not been confirmed. This medicine can be used in children older than two years or it cannot be used in children with body weight less than 30 kg (66.1 lb).

Lorahist Side-effects

The following side-effects may commonly occur in children when using Lorahist Tablet. Discuss with your doctor if any of these side-effects last for a long time or are severe:
Rarely, the use of Lorahist Tablet may cause the following side-effects:
The following severe side-effects may also occur when using Lorahist Tablet:
  • heart diseases such as fast or irregular heartbeat
    If this happens, consult with your doctor.
  • liver diseases (such as abnormal liver function, jaundice, liver injury and inflammation of the liver)
    If such side-effect occurs, consult with your doctor.
  • If this happens, consult with your doctor.
  • severe allergic reaction (anaphylaxis and erythema multiforme)
    Symptoms: swelling of the lips, swelling of the face, swelling of the tongue, swelling of the throat, difficulty breathing due to narrowing of airways, shock, collapse, rash itching
    If this happens, stop taking this medicine and contact your doctor immediately.
  • Consult with the doctor if such side-effects occur.
  • abnormally heavy menstrual bleeding
    If this happens, consult with your doctor.
  • inflammation of the vagina (vaginitis)
    If such side-effect occurs, consult with your doctor.
Your doctor has prescribed this Lorahist because they have judged that the benefits outweigh the risks posed by side-effects. Many people using this medicine do not have serious side-effects. This is not a complete list of possible side-effects for Lorahist.
If you experience side-effects or notice other side-effects not listed above, contact your doctor for medical advice. You may also report side-effects to your local food and drug administration authority. You can look up the drug authority contact information from the Drug Authority Finder at TabletWise.com.

Side-effects and Allergic Reactions of Lorahist by Severity and Frequency

Infrequent and Rare Side-effects

Following are the infrequent and rare side-effects of this medicine:

Severe Side-effects

Following are the severe side-effects of this medicine:

Side-effects in Children

Following are the side-effects of this medicine in young patients:

Serious Allergic Reactions

Following are the symptoms of serious allergic reactions to this medicine:
  • collapse
  • difficulty breathing due to narrowing of airways
  • itching
  • rash
  • shock
  • swelling of the face
  • swelling of the lips
  • swelling of the throat
  • swelling of the tongue
If these symptoms occur then stop taking Lorahist and contact your doctor immediately.
If you experience side-effects or notice other side-effects not listed above, contact your doctor for medical advice. You may also report side-effects to your local food and drug administration authority. You can look up the drug authority contact information from the Drug Authority Finder at TabletWise.com.

Warnings

Skin tests

Patients undergoing skin tests are at an increased risk when using this medicine. This medicine may prevent or reduce the positive results of skin reactivity index which results in wrong results of skin tests. This medicine should be stopped at least 48 hours before undergoing skin tests.

Pregnancy or breastfeeding

Patients who are pregnant or breastfeeding are at an increased risk when using this medicine. These patients should consult with a doctor before using Lorahist.

Liver disease

Patients with liver disease are at an increased risk when using this medicine. Consult your doctor if you have a liver disease. Your doctor may change the dose according to your need.

Kidney disease

Patients with kidney disease are at an increased risk when using this medicine. Consult your doctor if you have a kidney disease. Your doctor may change the dose according to your need.

Drowsiness

Patients using more than the directed dose of Lorahist are at an increased risk. These patients may develop drowsiness. Do not take more than the recommended dose.

Allergy to Lorahist

Patients who are allergic to Lorahist are at an increased risk when using this medicine. In such patients, an allergic reaction may develop. If this happens, stop using this medicine and seek medical help immediately.

Family history

Patients with rare genetic problems such as Lapp lactase deficiency, galactose intolerance, and decreased absorption of glucose-galactose are at an increased risk when using this medicinal product that contains lactose. These patients should not take Lorahist.

Interactions with Lorahist

When two or more medicines are taken together, it can change how the medicines work and increase the risk of side-effects. In medical terms, this is called as a Drug Interaction.
Lorahist Tablet may interact with cytochrome P450 3A4 (CYP3A4) inhibitors. When Lorahist is used with CYP3A4 inhibitors, the amount of Lorahist increases in the body and results in more chances of adverse events.
There may be an interaction of Lorahist with cytochrome P450 2D6 (CYP2D6) inhibitors. When Lorahist is used with CYP2D6 inhibitors, it results in an increased amount of Lorahist and adverse events of Lorahist.
Lorahist Tablet interacts with erythromycin, which is used to treat bacterial infection. When Lorahist is used with erythromycin, the amount of Lorahist increases in the blood and the amount of erythromycin decreases in the blood.
Special instructions need to be followed while taking this medicine along with cimetidine, which is used to treat heartburn and stomach ulcers. The use of Lorahist with cimetidine may increase the amount of Lorahist in the blood.
Your doctor's guidelines may need to be followed while taking this medicine along with ketoconazole, which is used to treat fungal infection. The amount of Lorahist in the blood may increases when taken with ketoconazole.
This page does not contain all the possible interactions of Lorahist Tablet. Share a list of all medicines that you use with your doctor and pharmacist. Do not start, stop, or change the dose of any medicines without the approval of your doctor.

Interactions of Lorahist by Severity

Serious

The following medicines may interact when taken together and can cause harmful effects in the body. Please consult with your doctor or pharmacist before taking these medicines together.

Moderate

The following medicines may interact when taken together and can increase your risk of harmful effects. Please consult with your doctor or pharmacist before taking these medicines together.

When should Lorahist be not used?

Allergy

This medicine should not be used in patients with known allergic reaction to it. These patients are at an increased risk of severe allergic reaction. These patients may have the following symptoms if they use this medicine:
  • severe itching
  • red or purple coloured spots on the skin
  • hives
  • rash
  • photosensitivity reaction
  • swelling due to the fluid accumulation
  • severe allergic reaction (anaphylaxis)

Children under the age of two years

The safety and effectiveness of Lorahist in children under the age of two years have not been confirmed. So, this medicine should not be used in these patients.

Expired Medication

Taking a single dose of expired Lorahist is unlikely to cause a side-effect. However, please discuss with your doctor or pharmacist, if you feel unwell or sick. An expired medicine may become ineffective in treating your prescribed conditions. To be on the safe side, it is important not to use an expired drug. You are much safer by always keeping a fresh supply of unexpired medicines.

Safe Disposal of Medication

  • If there are disposal instructions on the package, please follow the instructions.
  • If there are medicine take-back programs in your country, you should contact the respective authority to arrange for the disposal of the medicine. For example, in the USA, the Drug Enforcement Administration regularly hosts National Prescription Drug Take-Back events.
  • If there are no take-back programs, mix the medicine with dirt and place them in a sealed plastic bag. Throw the plastic bag in your household trash. Separately, remove all personal information including the prescription label from the medicine packaging and then dispose off the container.
  • If specifically indicated on the medicine package that it needs to be flushed down the toilet when no longer needed, perform the required step.
This page provides information for Lorahist Tablet .
Allergy
Allergic Rhinitis
Hives
Hay Fever

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