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Proof of Big Pharma corruption: Now we're all told we should have the cholesterol levels of a newborn (achieved through prescription medication, of course)

Sunday, December 10, 2017 -- (Natural News) The medical establishment is still trying really hard to push the lie that all cholesterol is evil, and that the only way for a person to stay healthy is to completely remove all cholesterol from his or her body. And a recent study out of the United Kingdom says people should do this... Read More

Do Statins for High Cholesterol Decrease Deaths from Heart Disease?

Friday, December 08, 2017 -- An article published in the British Medical Journal discusses a study on the long-term use of statins for patients with high cholesterol. A recent study explored the long-term use of statins in patients with high levels of low-density lipoprotein (LDL) cholesterol. LDL cholesterol transports fat to cells, where they can build up and cause atherosclerosis. […] The post Do Statins for High Cholesterol Decrease Deaths from Heart Disease? appeared first on Medical News Bulletin | Health News and Medical Research.

Are Extremely High Levels of HDL Cholesterol Safe?

Tuesday, December 12, 2017 -- Researchers investigated whether extremely high levels of HDL cholesterol are associated with increased mortality in men and women. HDL cholesterol, often known as “good” cholesterol, is known to have an inverse relationship with cardiovascular disease and mortality—higher HDL cholesterol levels are associated with lower cardiovascular disease. Randomized clinical trials, however, have failed to prove that […] The post Are Extremely High Levels of HDL Cholesterol Safe? appeared first on Medical News Bulletin | Health News and Medical Research.

Dexamethasone inhibits activation of monocytes/macrophages in a milieu rich in 27-oxygenated cholesterol

Wednesday, December 13, 2017 -- by Bo-Young Kim, Yonghae Son, Jeonga Lee, Jeongyoon Choi, Chi Dae Kim, Sun Sik Bae, Seong-Kug Eo, Koanhoi Kim Molecular mechanisms underlying the decreased number of macrophages and T cells in the arteries of cholesterol-fed-rabbits following dexamethasone administration are unknown. We investigated the possibility that dexamethasone could affect activation of monocytic cells induced by oxygenated derivatives of cholesterol (oxysterols) using THP-1 monocyte/macrophage cells. 27-Hydroxycholesterol (27OHChol), an oxysterol elevated with hypercholesterolemia, enhanced production of CCL2, known as MCP1, chemokine from monocytes/macrophages and migration of the monocytic cells, but the CCL2 production and the cell migration were reduced by treatment with dexamethasone. Dexamethasone inhibited superproduction of CCL2 induced by 27OHChol plus LPS and attenuated transcription of matrix metalloproteinase 9 as well

Normal LDL-Cholesterol Levels Are Associated With Subclinical Atherosclerosis in the Absence of Risk Factors

Monday, December 11, 2017 -- AbstractBackground Absence of cardiovascular risk factors (CVRFs) is traditionally considered low risk for atherosclerosis; however, individuals without CVRFs, as currently defined, still have events. Objectives This study sought to identify predictors of subclinical atherosclerosis in CVRF-free individuals. Methods Participants from the PESA (Progression of Early Subclinical Atherosclerosis) study (n = 4,184) without conventional CVRFs were evaluated (n = 1,779; 45.0 ± 4.1 years, 50.3% women). CVRF freedom was defined as no current smoking and untreated blood pressure <140/90 mm Hg, fasting glucose <126 mg/dl, total cholesterol <240 mg/dl, low-density lipoprotein cholesterol (LDL-C) <160 mg/dl, and high-density lipoprotein cholesterol ≥40 mg/dl. A subgroup with optimal CVRFs (n = 740) was also defined as having blood pressure <120/80 mm Hg, fasting glucose <100 mg/dl, glycosylated hemoglobin <5.7%, and total cholesterol <200 mg/dl. We evaluated ultrasound-detected carotid, iliofemoral, and abdominal aortic plaques; coronary artery calcification; serum biomarkers; and

Early Atherosclerosis Defies 'Normal' Cholesterol (CME/CE)

Tuesday, December 12, 2017 -- (MedPage Today) -- Subclinical plaque rampant even in healthy people with LDL-C in range

Xarelto for CAD/PAD? LVAD Cord Out the Head; HDL Drug Moves Forward

Monday, December 11, 2017 -- (MedPage Today) -- Recent developments of interest in cardiovascular medicine