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    Inovios DNA Immunotherapy Demonstrates Immune Response Results Key in Treating Chronic Hepatitis B Infection

    Wednesday, March 14, 2018 -- PLYMOUTH MEETING, Pa., March 14, 2018 -- Inovio Pharmaceuticals, Inc. (NASDAQ:INO) today announced that interim Phase 1 results show its DNA immunotherapy designed to treat hepatitis B virus (HBV) infection was safe,...

    HBV genotype, antigen status correlate with RNA levels

    Wednesday, March 14, 2018 -- Factors associated with serum hepatitis B RNA levels include HBV e antigen status, serum alanine aminotransferase, HBV genotype and the presence of basal core promoter mutations, according to recently published data from a multi-ethnic cohort study.“HBV RNA in serum is a novel and promising marker for [covalently closed circular DNA (cccDNA)] transcriptional activity and could thus be used to monitor response for currently available treatment, but in particular for future HBV treatments targeting the HBV life cycle,” Margo J.H. van Campenhout, MD, from the Erasmus MC University