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Study Finds HPV-Related Respiratory Disease Prevented by Vaccine

Wednesday, November 15, 2017 -- Researchers have found that human papillomavirus (HPV) vaccine may also protect against recurrent respiratory papillomatosis, a rare, but incurable childhood respiratory disease.
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[Comment] The importance of HPV16 in anal cancer prevention

Friday, November 17, 2017 -- Like cervical cancer, anal cancer and its direct precursor lesion, high-grade anal intraepithelial neoplasia (AIN), are caused by persistent infections with human papillomaviruses (HPV).1 The natural history of HPV in cervical cancer has been comprehensively investigated. In the more than 40 HPV types infecting the anogenital tract, high-risk HPV-types and possible or probable high-risk types for the development of cervical cancer have been defined.2 Cervical cancer is preventable by regular screening.

Apparent Diffusion Coefficient Histograms of Human Papillomavirus-Positive and Human Papillomavirus-Negative Head and Neck Squamous Cell Carcinoma: Assessment of Tumor Heterogeneity and Comparison with Histopathology [HEAD & NECK]

Wednesday, November 15, 2017 -- BACKGROUND AND PURPOSE: Head and neck squamous cell carcinoma associated with human papillomavirus infection represents a distinct tumor entity. We hypothesized that diffusion phenotypes based on the histogram analysis of ADC values reflect distinct degrees of tumor heterogeneity in human papillomavirus–positive and human papillomavirus–negative head and neck squamous cell carcinomas. MATERIALS AND METHODS: One hundred five consecutive patients (mean age, 64 years; range, 45–87 years) with primary oropharyngeal (n = 52) and oral cavity (n = 53) head and neck squamous cell carcinoma underwent MR imaging with anatomic and diffusion-weighted sequences (b = 0, b = 1000 s/mm2, monoexponential ADC calculation). The collected tumor voxels from the contoured ROIs provided histograms from which position, dispersion, and form parameters were
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[Articles] Human papillomavirus types from infection to cancer in the anus, according to sex and HIV status: a systematic review and meta-analysis

Friday, November 17, 2017 -- HPV16 is by far the most carcinogenic HPV type in the anus, with enrichment of HPV16 even from high-grade lesions to anal cancer, both in individuals who are HIV negative and those who are HIV positive. Nevertheless, the fraction of anal cancer attributable to HPV16 is smaller in the HIV-positive population.

Human papillomavirus types from infection to cancer in the anus, according to sex and HIV status: a systematic review and meta-analysis

Monday, November 20, 2017 -- There are about 20 000 new cases of anal cancer per year globally, of which an estimated 90% are caused by human papillomavirus (HPV) infection. New research by scientists from the International Agency for Research on Cancer (IARC), published today in The Lancet Infectious Diseases, characterizes the contribution of different oncogenic HPV types to the development of anal cancer, in HIV-negative men and women as well as in high-risk HIV-positive populations. Lin C, Franceschi S, Clifford GM Human papillomavirus types from infection to cancer in the anus, according to sex and HIV status: a systematic review and meta-analysis Lancet Infect Dis, Published online 17 November 2017; http://dx.doi.org/10.1016/S1473-3099(17)30653-9

HPV Vaccine Tied to Reduced Respiratory Papillomatosis Rate

Thursday, November 16, 2017 -- Reduction in incidence of juvenile-onset recurrent respiratory papillomatosis from 2012 to 2016
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