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Leroy Tablet

Generic Name(s): Levofloxacin

Why it's used

Leroy Tablet is used to treat pneumonia. It is a prescription medicine. It is also used to treat sinus infections. Leroy is also used to treat severe cases of bronchitis. Leroy Tablet is also used to treat certain other kinds of bacterial infections in the body, such as, on the skin, prostate, urinary tract, bladder and kidneys. Leroy Tablet is also used to treat certain potentially fatal infectious diseases, including, anthrax.
When not to use
Leroy Tablet will not work against viral infections such as the common cold or flu.
Fluoroquinolone Antibacterial
Leroy belongs to a class of medicines called Fluoroquinolone Antibacterial. Fluoroquinolones are medicines used for the treatment and prevention of certain types of bacterial infections. These medicines are commonly used to treat respiratory and urinary tract infections.

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How to use

Follow directions on the product label, information guide, and provided by your doctor before using Leroy. Use this medicine as per your doctor's instructions.
Leroy is used with or without food. Drink plenty of fluids while taking this medicine to avoid crystal formation in urine and formation of highly concentrated urine.

Typical Dosage

The typical adult dose of Leroy is 250-750 mg every 24 hours. The typical dose for children is 8 mg per kg/3.5 mg per lb of weight every 12 hours with a maximum of 250 mg per dose. This medicine is commonly used for a period of 7-14 days for pneumonia, 7 days for bronchitis, 28 days for swelling of the prostate, and 10 days for kidney infections. Leroy is typically used at the same time every day. There are no known habit-forming tendencies with this medicine.
This medicine should be used on an as-needed basis. You should continue to use this medicine as directed by the doctor even if you feel well.
The injection form of this medicine is to be slowly injected in the veins. The injection form of the medicine should not be used on the muscle, body cavity, spinal cord, or skin

Talk to Your Doctor

Tell your doctor if you develop new symptoms. If you have any kidney disease, a lower dosage of Leroy may be recommended if you suffer from kidney disease.

Use in Children

If you are giving Leroy Tablet to a child, be sure to use a product that is meant for use in children. Before giving this medicine, use the child's weight or age to find the right dose from the leaflet or product package. You can also read the dosage section of this page to know the correct dose for your child. Else, consult with your doctor and follow their recommendation.

Lab Tests

Your doctor may require that certain tests be performed before using Leroy Tablet. The doctor may ask you to have Antibiotic Susceptibility test. This test is required to determine the specific bacterial infection.

Storage

Store Leroy Tablet at 15-30°C (59°F to 86°F), away from excess moisture, and away from light. Keep this medicine away from children and pets.
Medicines may be given for uses other than those listed in the medicine guide. Do not use Leroy Tablet for symptoms for which it was not prescribed. Do not give Leroy Tablet to others who may have similar symptoms as you. Self-medication can cause harm.

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How to take Leroy

Your dose may depend on several personal factors. You should consult with your doctor to find out the dose that is best for you. The dose of Leroy depends on the following factors:
  • patient's weight
  • patient's health
  • the health of the patient's liver
  • medicines recommended by your doctor
  • any other medicines in use
  • herbal supplements consumed

Leroy Dosage

Dosage for pneumonia from a hospital infection

Adult
  • Recommended: 750 mg every 24 hours for 7-14 days

Dosage for pneumonia not originating from a hospital

Adult
  • Recommended: 500 mg every 24 hours for 7-14 days or 750 mg every 24 hours for 5 days depending on the type of bacteria causing the infection

Dosage for severe cases of sinusitis

Adult
  • Recommended: 750 mg every 24 hours for 5 days or 500 mg every 24 hours for 10-14 days

Dosage for long-term bronchitis caused by infections

Adult
  • Recommended: 500 mg every 24 hours for 7 days

Dosage for skin infections (complicated)

Adult
  • Recommended: 750 mg every 24 hours for 7-14 days

Dosage for skin infections (uncomplicated)

Adult
  • Recommended: 500 mg every 24 hours for 7-10 days

Dosage for swelling of the prostate gland due to infections

Adult
  • Recommended: 500 mg every 24 hours for 28 days

Dosage for inflammation of the kidney and urinary tract infections

Adult
  • Recommended: 750 mg every 24 hours for 5 days or 250 mg every 24 hours for 10 days depending on the type of bacteria causing the infection

Dosage for inhalational anthrax

Adult
  • Recommended: 500 mg every 24 hours for 60 days
Children (less than 50 kg weight and more than or equal to 6 months of age)
  • Recommended: 8 mg per kg/3.6 mg per lb of weight every 12 hours for 60 days
  • Maximum: 250 mg per dose
Children (children more than 50 kg weight and more than or equal to 6 months of age)
  • Recommended: 500 mg every 24 hours for 60 days

Dosage for urinary tract infections (uncomplicated)

Adult
  • Recommended: 250 mg every 24 hours for 3 days

Dosage for inflammation of the urinary bladder

Adult
  • Recommended: 250 mg once daily for 3 days

Minimum Age

6 months

Dosage calculation for children

To calculate the dosage for children please use the weight based dose calculator to calculate the appropriate dosage as per the weight of your child.

Forms

Tablets
Strength: 250 mg, 500 mg, 750 mg
Oral Solution
Strength: 25 mg/mL
Injection: single-use vials for dilution
Strength: 500 mg in 20 mL, 750 mg in 30 mL
Injection: premix single-use flexible containers
Strength: 250 mg in 50 mL, 500 mg in 100 mL, 750 mg in 150 mL

Special Instructions

Oral Solution
Oral solution should be taken one hour before or two hours after the meal.
Injection
Injection should be infused into the veins slowly over a period of not less than 60 or 90 minutes.

Missed Dose

A missed dose should be taken as early as you remember it. However, if the time for the next dose is almost there, then the missed dose should be skipped, and the regular dosing schedule should be continued.

Overdose

What to do if you overdose on Leroy?
If you have taken more than the recommended dose of Leroy get medical advice immediately. Antacids are recommended for the protection of the mucous membrane layer of the stomach.
Symptoms of an overdose of Leroy
If you use too much of this medicine, it could lead to dangerous levels of the medicine in your body. In such cases, symptoms of an overdose may include:
If you think you have overdosed on Leroy Tablet, call a poison control center immediately. You can look up the poison control center information from the Poison Center Finder at TabletWise.com.

Precautions while using Leroy

Before you use Leroy, tell your doctor of your medical and health history including the following:
  • bone and joint problems
  • central nervous system problems
  • heart failure
  • heart transplant
  • high blood glucose
  • kidney problems
  • kidney transplant
  • liver problems
  • low potassium level in the blood
  • lung transplant
  • nerve problems
  • palpitations
  • seizures
  • slow heart rate
  • swollen and painful joints (rheumatoid arthritis)
  • tendon problems
Patients with kidney failure, rheumatoid arthritis, kidney, lung or heart transplant are at an increased risk of inflammation of the tissue connecting bone to muscle (tendinitis) and tendon rupture. Patients with a low potassium level in the blood, slow heart rate, or heart failure are at an increased risk of palpitations and loss of consciousness.
Before you use Leroy Tablet, tell your doctor if you are allergic to it or its ingredients. Your doctor may prescribe an alternative medicine and update your medical records to record this information.
The use of this medicine may change blood clotting time. Using Leroy with warfarin increases the bleeding episodes. Patients should be monitored for the blood clotting parameters (the international normalized ratio (INR), prothrombin time, or other anticoagulation tests) along with evidence of bleeding.
The use of Leroy Tablet may change blood sugar. Using Leroy with antidiabetic agents may cause either increase or decrease the blood sugar levels. Patients should be monitored carefully for blood glucose levels.

Use in Pregnancy

Leroy Tablet is not safe for use in pregnant women. If you are pregnant or planning to become pregnant, you should discuss with your doctor the impact this medicine may have on the baby before you start to use this medicine. There are not enough and well-controlled studies in pregnant women. This medicine should be used during pregnancy only if the potential benefit to the mother justifies the potential risk to the fetus.

Use while Breastfeeding

Leroy is not safe for use in women who are breastfeeding. If you are breastfeeding, discuss with your doctor if you should either discontinue breastfeeding or stop using this medicine while breastfeeding. Leroy may pass into breast milk which may cause serious side effects to infants. This medicine should be used only after considering the importance of the drug to the mother.

Impact on Fertility

Consult with your doctor on the use of Leroy Tablet, if you are trying to conceive. Animal studies show that this medicine does not impact fertility. To be sure, discuss with your doctor.

Seizures

Leroy Tablet can make you feel sleepy. Be careful while driving, using machinery, or doing any other activity that needs you to be alert. The consumption of alcohol with Leroy Tablet can make you feel more sleepy. Leroy Tablet may cause seizures in some people. Discuss with your doctor if you perform activities where a loss of consciousness may cause you or others harm.

Increased Risk

This medicine may increase your sensitivity to sunlight. If this happens, limit your time outdoors and prevent sunburns. Cover your skin or use a sunscreen.

Side-effects in Children

Leroy Tablet may cause an increased risk of side-effects in younger patients. Children using this medicine may see an increased risk of pain in joints (arthralgia), arthritis, illness of the muscle connecting to the bone (tendon disorders), and walking abnormality.

Side-effects in Older Patients

Leroy Tablet may increase side-effects in older patients. Elderly patients may see an increased risk of tendon disorders, inflammation of the tissue connecting bone to muscle (tendinitis), inflammation of the liver (hepatitis), heart rhythm disorders, and low level of potassium in the blood.

Long Term Use

Clinical data for safety and effectiveness of using this medicine beyond 28 days in adults and beyond 14 days in children have not been confirmed.

Leroy Side-effects

The following side-effects may commonly occur when using Leroy Tablet. If any of these side-effects worsen or last for a long time, you should consult with your doctor:
Rarely, the use of Leroy Tablet may cause the following side-effects:
The following severe side-effects may also occur when using Leroy Tablet:
  • Changes in sensation and possible nerve damage (peripheral neuropathy) (permanent nerve damage)
    Symptoms: pain, burning, tingling, numbness weakness
    The patient should discontinue the medicine.
  • Intestine infection (pseudomembranous colitis) (possibly fatal)
    Symptoms: diarrhea, bloody stools, stomach cramps fever
    Call your doctor right away if you get these symptoms.
  • Serious allergic reactions (possibly fatal)
    Symptoms: hives, trouble breathing or swallowing, swelling of the lips, swelling of the tongue, swelling of the face, abnormal voice changes (hoarseness), rapid heartbeat, fainting, yellowing of the skin or eyes throat tightness
    This medicine should be discontinued.
  • Central nervous system effects
    Symptoms: seizures, hallucinations, restlessness, tremors, nervousness, confusion, depression, insomnia, nightmares, lightheadedness, feeling of fearful thoughts (paranoia) suicidal thoughts or acts
  • Liver damage (possibly fatal)
    Symptoms: nausea, vomiting, stomach pain, fever, weakness, itching, unusual tiredness, loss of appetite, light colored bowel movements, yellowing of the skin, yellowing of the whites of the eyes dark-colored urine
  • Serious heart rhythm changes (QT prolongation and torsades de pointes) (possibly fatal)
    Symptoms: abnormal heartbeat fainting
    Tell your doctor right away if you have an irregular or fast heartbeat or if you faint.
  • Changes in blood sugar
    Follow the doctor's instructions for how often to check the blood sugar. Stop taking Leroy and call your doctor right away if you get low blood sugar and you have diabetes while taking Leroy. Your medicine may need to be changed.
  • Sensitivity to sunlight (photosensitivity)
    Symptoms: sunburn blisters or swelling of the skin
    If you get any of these symptoms while taking Leroy, call your doctor right away. If you have to be in sunlight, use a sunscreen and wear clothes and a hat that covers your skin.
  • Joint problems such as arthritis
    Symptoms: pain, swelling, or inflammation of a tendon weakness or inability to use one of the joint
    The medicine should be discontinued. In the case of children, tell your child’s doctor if they have any joint problems during or after treatment with Leroy. Call your doctor right away at the first sign of tendon swelling, pain, or inflammation.
Your doctor has prescribed this Leroy because they have judged that the benefits outweigh the risks posed by side-effects. Many people using this medicine do not have serious side-effects. This is not a complete list of possible side-effects for Leroy.
If you experience side-effects or notice other side-effects not listed above, contact your doctor for medical advice. You may also report side-effects to your local food and drug administration authority. You can look up the drug authority contact information from the Drug Authority Finder at TabletWise.com.

Warnings

Patients Over 60 Years

Elderly patients are at an increased risk when using this medicine. Such patients may have an increased risk of inflammation of the tissue connecting bone to muscle (tendinitis), tendon rupture, liver damage and prolonged heartbeat. Patients should discontinue this medicine on the occurrence of hepatitis, pain, inflammation, swelling, or tendon rupture. Patients should be advised to take rest at the first sign of tendon rupture and contact the doctor for changing their medicine.

Patients Undergoing Corticosteroid Therapy

Patients taking corticosteroid drugs are at an increased risk when using this medicine. Such patients may have an increased risk of tendinitis and tendon rupture. Patients should discontinue this medicine on the occurrence of hepatitis, pain, inflammation, swelling, or tendon rupture. Patients should be advised to take rest at the first sign of tendon rupture and contact the doctor for changing their medicine.

Kidney Transplantation

Patients with a kidney transplant are at an increased risk when using this medicine. Such patients may have an increased risk of tendinitis and tendon rupture. Patients should discontinue this medicine on the occurrence of hepatitis, pain, inflammation, swelling, or tendon rupture. Patients should be advised to take rest at the first sign of tendon rupture and contact the doctor for changing their medicine.

Heart Transplantation

Patients with heart transplant are at an increased risk when using this medicine. Such patients may have an increased risk of tendinitis and tendon rupture. Patients should discontinue this medicine on the occurrence of hepatitis, pain, inflammation, swelling, or tendon rupture. Patients should be advised to take rest at the first sign of tendon rupture and contact the doctor for changing their medicine.

Lung Transplantation

Patients with lung transplants are at an increased risk when using this medicine. Such patients may have an increased risk of tendinitis and tendon rupture. Patients should discontinue this medicine on the occurrence of hepatitis, pain, inflammation, swelling, or tendon rupture. Patients should be advised to take rest at the first sign of tendon rupture and contact the doctor for changing their medicine.

Difficult Physical Activity

Patients performing a difficult physical activity are at an increased risk when using this medicine. Such patients may have an increased risk of tendinitis and tendon rupture. Patients should discontinue this medicine on the occurrence of hepatitis, pain, inflammation, swelling, or tendon rupture. Patients should be advised to take rest at the first sign of tendon rupture and contact the doctor for changing their medicine.

Kidney Failure

Patients with kidney failure are at an increased risk when using this medicine. Such patients may have an increased risk of tendinitis and tendon rupture. Patients should discontinue this medicine on the occurrence of hepatitis, pain, inflammation, swelling, or tendon rupture. Patients should be advised to take rest at the first sign of tendon rupture and contact the doctor for changing their medicine.

History of Tendon Disorders

Patients with a history of tendon disorders such as swollen and painful joints (rheumatoid arthritis) are at an increased risk when using this medicine. Such patients may have an increased risk of tendinitis and tendon rupture. Patients should discontinue this medicine on the occurrence of hepatitis, pain, inflammation, swelling, or tendon rupture. Patients should be advised to take rest at the first sign of tendon rupture and contact the doctor for changing their medicine.

Quinolones Drug Therapy

Patients taking quinolones drug are at an increased risk when using this medicine. These patients are at an increased risk of fatal allergic reactions (itching and swelling of the skin), sun-allergic reactions, seizure, loss of consciousness, and central nervous system effects such as convulsions, substance-induced mental disorder, confusion, depression and nightmares. Such patients should discontinue this medicine on the appearance of symptoms of neuropathy, sun-allergic reactions, hepatitis, central nervous system effects and at the first appearance of an allergic reaction. Treatment of serious allergic reaction include antihistamines, corticosteroids, pressor amines, epinephrine drug therapy along with oxygen, intravenous fluids, and airway management, as recommended by the doctor.

Bacterial Infection in the Colon

Patients with a bacterial infection in the colon are at an increased risk when using this medicine. Such patients may experience worsening of the bacterial infection on using this medicine. Patients should discontinue this medicine on worsening of their infection.

Palpitations and Decreased Potassium Levels

Patients with palpitations and decreased levels of the potassium in the blood are at an increased risk when using this medicine. These patients are at an increased risk of drug-associated effects on the heartbeat while using this medicine. Such patients should not use this medicine.

Children

Children using Leroy are at an increased risk when using this medicine. These patients are at increased risk of pain in joints, arthritis, tendon disorders and, a movement disorder.

Diabetic Patients

Patients with diabetes are at increased risk when using this medicine. These patients may experience either increase or decrease in their blood glucose levels. This medicine should be discontinued and suitable therapy has to be started in such patients.

Absence of a Bacterial Infection

Patients with absence bacterial infection are at an increased risk when using this medicine. These patients may experience ineffectiveness of medicine against bacteria.

Women

Women are at an increased risk when using this medicine. These patients are more sensitive to medicine-associated effects. Such patients should use this medicine cautiously.

Interactions with Leroy

When two or more medicines are taken together, it can change how the medicines work and increase the risk of side-effects. In medical terms, this is called as a Drug Interaction.
This page does not contain all the possible interactions of Leroy Tablet. Share a list of all medicines that you use with your doctor and pharmacist. Do not start, stop, or change the dose of any medicines without the approval of your doctor.

Didanosine

Your doctor's guidelines may need to be followed while taking this medicine along with didanosine, which is used to control conditions caused by HIV/AIDS. This medicine reduces the absorption of Leroy. Didanosine should not be taken within the two-hour period before or after taking Leroy.

Metal Cations

Leroy Tablet interacts with metal cations such as iron and magnesium. This medicine reduces the absorption of Leroy. Metal cations should be taken within the two-hour period before or after taking Leroy.

Sucralfate

There may be an interaction of Leroy with sucralfate, which is used to treat acid backflow from the stomach to food pipe (gastroesophageal reflux disease) and duodenal ulcers. This medicine reduces the absorption of Leroy. Sucralfate should be taken within the two-hour period before or after taking Leroy.

Antacids

Leroy Tablet may interact with antacids containing calcium, magnesium, or aluminum, which are used to relieve heartburn, indigestion or an upset stomach. This medicine reduces the absorption of Leroy. The patient should take antacids within the two-hour period before or after taking Leroy.

Multivitamins Containing Zinc

Special instructions need to be followed while taking this medicine along with multivitamins containing zinc, which is used to treat vitamin deficiency due to poor diet, certain illnesses, alcoholism, or during pregnancy. This medicine reduces the absorption of Leroy. The patient should take multivitamins within the two-hour period before or after taking Leroy.

Urine Screening Test

Your doctor's guidelines may need to be followed while taking this medicine along with a urine test. False positive urine screening tests for opiates have been reported in patients who were receiving fluoroquinolones. Another confirmatory test should be conducted to verify the results.

Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)

Leroy Tablet interacts with nonsteroidal anti-inflammatory drugs, which are used to treat painful and stiff joints (osteoarthritis) and swollen and painful joints (rheumatoid arthritis). When Leroy is used with NSAIDS, it may increase the risk of shaking body movements (convulsive seizures). It may also increase the risk of central nervous system stimulation which may lead to tremors, restlessness, nervousness, lightheadedness, confusion, hallucinations, feeling of fearful thoughts (paranoia), depression, nightmares, insomnia, and rarely suicidal thoughts or acts.

Theophylline

Special instructions need to be followed while taking this medicine along with theophylline, which is used to treat asthma and respiratory illness such as bronchitis. Using theophylline and fluoroquinolones together may increase the levels of theophylline in the blood which may lead to increased theophylline associated side effects. When Leroy is used with theophylline, the levels of theophylline should be monitored and appropriate dosage adjustments should be made.

Antidiabetic Agents

There may be an interaction of Leroy with antidiabetic agents which are used to treat high blood glucose. Using Leroy with antidiabetic agents may increase or decrease the blood glucose levels. When using both medicines together, it is recommended to monitor blood glucose carefully.

Warfarin

Leroy Tablet may interact with warfarin, which is used to treat and prevent harmful blood clots. Leroy increases the effects of warfarin. Patients should have blood tests such as prothrombin time, international normalized ratio and other suitable anticoagulation tests while using both medicines together.

Probenecid

Leroy Tablet may interact with probenecid, which is used to treat red, painful, hot, and swollen joints (gout) and increased uric acid in the blood (hyperuricemia). When Leroy is used with probenecid, it decreases the elimination of Leroy from the body. Patients should be cautious when Leroy is used with probenecid.

Antiarrhythmic Agents

Your doctor's guidelines may need to be followed while taking this medicine along with antiarrhythmic agents (quinidine, procainamide, amiodarone, sotalol), which are used to treat abnormal heart rhythms. When Leroy is used with antiarrhythmic agents, it may cause palpitations. Patients should avoid taking both drugs together.

QT Interval Prolongation Drugs

Special instructions need to be followed while taking this medicine along with Drugs known to prolong QT interval (tricyclic antidepressants, macrolides, and antipsychotics). It results in the prolongation of the heartbeat (prolong QT interval). Patients should be cautious when Leroy is used with the drugs that cause prolonged heartbeat.

Cyclosporine

Leroy Tablet interacts with cyclosporine, which is used to prevent organ rejection in liver, kidney, or heart transplant. When Leroy is used with cyclosporine, it may increase the level of cyclosporine in the blood.

Cimetidine

There may be an interaction of Leroy with cimetidine, which is used to treat ulcer and gastroesophageal reflux disease. It interferes with the elimination of Leroy. Patients should be cautious when Leroy is used with cimetidine.

Traveling With Medication

  • Ensure that you carry enough doses of each of your prescription medicines to last the entire trip. The best place to store your medicines is in the carry on baggage. However, while flying, if carrying liquid medicines, make sure you do not go over the limits imposed for carry-on liquids.
  • While traveling overseas, make sure that you can carry each of your prescription medicines legally to your destination country. One way to ensure this is by checking with your destination country's embassy or website.
  • Make sure that you carry each of your medicines in their original packaging, which should typically include your name and address, and the details of the prescribing doctor.
  • If your travel involves crossing time zones, and you are required to take your medicine as per a fixed schedule, make sure that you adjust for the change in time.

Expired Medication

Taking a single dose of expired Leroy is unlikely to cause a side-effect. However, please discuss with your doctor or pharmacist, if you feel unwell or sick. An expired medicine may become ineffective in treating your prescribed conditions. To be on the safe side, it is important not to use an expired drug. You are much safer by always keeping a fresh supply of unexpired medicines.

Safe Disposal of Medication

  • If there are disposal instructions on the package, please follow the instructions.
  • If there are medicine take-back programs in your country, you should contact the respective authority to arrange for the disposal of the medicine. For example, in the USA, the Drug Enforcement Administration regularly hosts National Prescription Drug Take-Back events.
  • If there are no take-back programs, mix the medicine with dirt and place them in a sealed plastic bag. Throw the plastic bag in your household trash. Separately, remove all personal information including the prescription label from the medicine packaging and then dispose off the container.
  • If specifically indicated on the medicine package that it needs to be flushed down the toilet when no longer needed, perform the required step.
This page provides information for Leroy Tablet .
Bacterial Infections
Pneumonia
Sinusitis
Bronchial Disorders

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