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Maxime Tablet

Generic Name(s): Cefixime

Why it's used

Maxime Tablet is used to treat certain bacterial infections including urinary tract infections, ear infections, throat infections including pharyngitis and tonsillitis, and sexually transmitted infections, such as, gonorrhea, that are affecting the urethra and rectum. It is a prescription medicine. Maxime is also used to treat worsening symptoms of severe cases of bronchitis.
When not to use
Maxime Tablet will not work to treat a viral infection, such as, a common cold or flu.
Cephalosporin Antibacterials
Maxime belongs to a class of medicines called Cephalosporin Antibacterials. Cephalosporins are antibacterial medicines that kill bacteria by interfering with how bacteria build their cell walls.

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How to use

Follow directions on the product label, information guide, and provided by your doctor before using Maxime. Consume this medicine as per your doctor's instructions.
Maxime is consumed with or without food.

Typical Dosage

The typical adult dose of Maxime is 400 mg daily or 200 mg every 12 hours. The typical dose for children is 400 mg daily if weighing more than 50 kg (or 12 years and older). Children less than 12 years old and more than 6 months old are to be given 8 mg per kg of body weight of this medicine daily. Maxime is typically used at the same time every day.
This medicine should be used on an as-needed basis. You should continue to use this medicine as directed by the doctor even if you feel well.
If using the liquid form of this medicine, measure the dose using the provided measuring cup, spoon, or dropper. Before pouring the medicine into the measuring device, you should check the measurement markings carefully. Then, pour the dose amount into the device. After use, clean and store the measuring device in a safe place for your next use. You should not use a tablespoon or teaspoon as the dose measuring devices since it can result in an incorrect dose. If indicated on the product package, shake the medicine before use.
If you are using the chewable tablet form of this medicine, make sure you chew the medicine before you swallow it.

Talk to Your Doctor

Tell your doctor if your condition does not improve or worsens. If you have any kidney disease, a low dose may be recommended by your doctor. Consult with your doctor before stopping the use of Maxime Tablet.
Taking a high dose of this medicine is known to increase the chances of side-effects.

Use in Children

If you are giving Maxime Tablet to a child, be sure to use a product that is meant for use in children. Before giving this medicine, use the child's weight or age to find the right dose from the leaflet or product package. You can also read the dosage section of this page to know the correct dose for your child. Else, consult with your doctor and follow their recommendation.

Storage

Store Maxime Tablet at room temperature 20° to 25°C (68-77°F) away from heat, and away from moisture. Keep this medicine away from children and pets.
Medicines may be given for uses other than those listed in the medicine guide. Do not use Maxime Tablet for symptoms for which it was not prescribed. Do not give Maxime Tablet to others who may have similar symptoms as you. Self-medication can cause harm.

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How to take Maxime

Your dose and how often you take Maxime will depend on the following factors:
  • age
  • weight
  • patient's health
  • the health of the patient's liver
  • medicines recommended by the doctor
  • any other medicines being used
  • herbal supplements in use

Maxime Dosage

Dosage for uncomplicated urinary tract infections

Adult (adults)
  • Recommended: 400 mg/day
Children (6 months or older)
  • Recommended: 8 mg per kg/3.6 mg per lb of body weight daily for oral suspension
Children (children over 12 years or weighing more than 50 kg)
  • Recommended: 400 mg/day
Children (weight between 5 - 6.2 kg (11.03 - 13.67 lb))
  • Recommended: 2.5 ml daily (100 mg/5 ml suspension) or 1.25 ml daily (200 mg/5 ml suspension)
Children (weight between 6.3 - 12.5 kg (13.89 - 27.56 lb))
  • Recommended: 5 ml daily (100 mg/5 ml suspension) or 2.5 ml daily (200 mg/5 ml suspension)
Children (weight between 12.6 - 18.8 kg (27.78 - 41.45 lb))
  • Recommended: 7.5 ml daily (100 mg/5 ml suspension) or 3.75 ml daily (200 mg/5 ml suspension)
Children (weight between 18.9-25 kg (41.67-55.12 lb))
  • Recommended: 10 ml daily (100 mg/5 ml suspension) or 5 ml daily (200 mg/5 ml suspension)
Children (weight between 25.1-31.3 kg (55.34-69.01 lb))
  • Recommended: 12.5 ml daily (100 mg/5 ml suspension) or 6.25 ml daily (200 mg/5 ml suspension)
Children (weight between 31.4-37.5 kg (69.23-82.67 lb))
  • Recommended: 15 ml daily (100 mg/5 ml suspension) or 7.5 ml daily (200 mg/5 ml suspension)
Children (weight between 37.6 -43.8 kg (82.89-96.56 lb))
  • Recommended: 17.5ml daily (100 mg/5 ml suspension) or 8.75 ml daily (200 mg/5 ml suspension)
Children (weight between 43.9 to 50 kg (96.78-110.23 lb))
  • Recommended: 20ml daily (100 mg/5 ml suspension) or 10ml daily (200 mg/5 ml suspension)

Dosage for middle ear infections

Adult (adults)
  • Recommended: 400 mg/day
Children (6 months or older)
  • Recommended: 8 mg per kg/3.6 mg per lb of body weight daily for oral suspension
Children
  • Recommended: 400 mg daily

Dosage for throat infections (pharyngitis or tonsillitis)

Adult (adults)
  • Recommended: 400 mg daily
Children (6 months or older)
  • Recommended: 8 mg per kg/3.6 mg per lb of body weight daily for oral suspension
Children (children over 12 years or weighing more than 50 kg)
  • Recommended: 400 mg daily

Dosage for worsening of severe bronchitis

Adult (adults)
  • Recommended: 400 mg/day
Children (6 months or older)
  • Recommended: 8 mg per kg/3.6 mg per lb of body weight daily for oral suspension
Children (children over 12 years or weighing more than 50 kg)
  • Recommended: 400 mg daily

Dosage for sexually transmitted infections (gonorrhea)

Adult (adults)
  • Recommended: 400 mg/day
Children (6 months or older)
  • Recommended: 8 mg per kg/3.6 mg per lb of body weight daily for oral suspension
Children (children over 12 years or weighing more than 50 kg)
  • Recommended: 400 mg/day

Minimum Age

6 months

Dosage calculation for children

To calculate the dosage for children please use the weight based dose calculator to calculate the appropriate dosage as per the weight of your child.

Forms

Tablet
Strength: 100 mg, 150 mg, 200 mg, 400 mg
Capsule
Strength: 100 mg, 150 mg, 200 mg, 400 mg
Oral suspension
Strength: 100 mg/5 ml, 200 mg/5 ml, 500 mg/5 ml
Chewable tablet
Strength: 100 mg, 150 mg, 200 mg, 400 mg

Missed Dose

Skip the missed dose and take the next dose as per your regular schedule.

Overdose

What to do if you overdose on Maxime?
An antidote is not available for Maxime. The effects of an overdose may be removed by the procedure called gastric lavage, which is used to clean out the contents of the stomach.
Symptoms of an overdose of Maxime
If you use too much of this medicine, it could lead to dangerous levels of the medicine in your body. In such cases, symptoms of an overdose may include:
If you think you have overdosed on Maxime Tablet, call a poison control center immediately. You can look up the poison control center information from the Poison Center Finder at TabletWise.com.

Precautions while using Maxime

Before you use Maxime, tell your doctor of your medical and health history including the following:
  • an inherited disorder that causes an increase in the level of phenylalanine in the blood (phenylketonuria)
  • inflammation of the digestive tract (colitis)
  • kidney disease
  • liver disease
Treatment with Maxime changes the normal state of the colon leading to overgrowth of bacteria in the intestine. This may result in mild diarrhea or in the worst case even cause a fatal inflammatory condition of the intestines.
Before you use Maxime, tell your doctor if you are allergic to it or its ingredients. Your doctor may prescribe an alternative medicine and update your medical records to record this information. Discuss with your doctor if you are allergic to cephalosporin antibiotics, or penicillin antibiotics.

Use when Pregnant

Maxime should be used only when required in patients who are pregnant or planning to become pregnant.

If Breastfeeding

Consult with your doctor on the use of Maxime Tablet during breastfeeding. It is unknown if this medicine passes into breast milk.

If trying to Conceive

Consult with your doctor on the use of Maxime, if you are trying to conceive.

Seizures

Maxime can make you feel sleepy. Be careful, especially while driving, while using heavy machinery, or when doing any activity that needs you to be completely alert. The consumption of alcohol with Maxime can worsen the sleepiness. Maxime may cause seizures in some people. Hence, you should discuss with your doctor before performing any activities where a loss of consciousness may cause harm to you or others.

Maxime Side-effects

The following side-effects may commonly occur when using Maxime Tablet. If any of these side-effects worsen or last for a long time, you should consult with your doctor:
The following side-effects may commonly occur in children when using Maxime Tablet. Discuss with your doctor if any of these side-effects last for a long time or are severe:
Rarely, the use of Maxime Tablet may cause the following side-effects:
  • an increase in the number of disease fighting white blood cells (eosinophilia)
  • blistering of the skin
  • decrease in the number of granulocytes, a type of white blood cells
  • dizziness
  • facial swelling
  • fever
  • headache
  • increase in platelet count
  • increase in prothrombin time
  • increase in the level of lactate dehydrogenase enzyme (LDH)
  • increase in the level of liver enzymes
  • inflammation in the kidney
  • itching of the skin
  • joint pain
  • liver disease
  • serious skin disorders
  • skin rashes
  • swelling of the lips, throat or tongue
  • temporarily increased level of waste products in the blood such as creatinine and blood urea nitrogen
  • vaginal itching
  • yeast infection
The following severe side-effects may also occur when using Maxime Tablet:
  • Disorder of the skin or mucous membrane called as Stevens-Johnson syndrome
    Symptoms: bleeding or blistering of the skin, flu-like symptoms fever
    If this happens, contact your doctor right away.
  • Inflammation of the colon (pseudomembranous colitis)
    Symptoms: severe watery diarrhea, feeling weak fever
    If this happens, contact your doctor right away and stop using this medicine.
  • Inflammation of the vagina, called as vaginitis
    Symptoms: itching in the vaginal area
    If this happens, contact your doctor right away.
  • An abnormal low level of a type of white blood cell (neutropenia)
  • A deficiency of platelets, red blood cells and white blood cells called as pancytopenia
  • Brain disease called as encephalopathy
    Symptoms: convulsions, confusion lack of consciousness
    If this happens, contact your doctor right away.
  • Severe skin reaction
    Symptoms: fever, chill, muscle pain severe blistering rash on the skin
    If this happens, contact your doctor right away.
  • Inflammation of the liver, called as hepatitis
  • Anemia due to an abnormal breakdown of the red blood cells (hemolytic anemia)
    Symptoms: nosebleeds, shortness of breath, bleeding gums, chills, pale skin tiredness
    If this happens, contact your doctor right away.
Your doctor has prescribed Maxime Tablet because they judge that the benefit is greater than the risk posed by side-effects. Many people using this medicine do not have serious side-effects. This page does not list all possible side-effects of Maxime Tablet.
If you experience side-effects or notice other side-effects not listed above, contact your doctor for medical advice. You may also report side-effects to your local food and drug administration authority. You can look up the drug authority contact information from the Drug Authority Finder at TabletWise.com.

Warnings

Prior Use of Maxime

Patients who are using this medicine again are at an increased risk with this medicine. These patients may have an increased risk of anemia.

Severe Skin-Related Side-Effects

Patients with severe skin related side-effects are at increased risk with this medicine. These patients may see an increase in white blood cell counts in the body. Use of the medicine should be discontinued in such a case.

Prolonged Treatment with Antimicrobial Therapy

Patients with antimicrobial therapy are at increased risk when using this medicine. A fall in prothrombin activity may occur in these patients. Monitor prothrombin time carefully and take vitamin K as indicated by your doctor. A fall in prothrombin time indicates that your blood clots faster than normal and possibly cause serious health issues.

Poor Functioning of Kidneys

Patients suffering from kidney related health issues are at increased risk when using this medicine. A fall in prothrombin activity may occur in these patients. This may indicate that your blood clots faster than normal and possibly cause serious health issues. Monitor prothrombin time carefully and your doctor may prescribe you to take vitamin K.

Maxime Use with Other Antimicrobial Agents

Patients using Maxime and other antimicrobial agents are at increased risk using this medicine. Such patients are at increased risk of developing diarrhea. If the patient suffers from diarrhea, treatment including fluid/electrolytes, protein supplementation, antibiotics, and a surgical evaluation should be given to the patient.

Strongly Suspected Bacterial Infection

Patients with strongly suspected bacterial infection are at increased risk when using Maxime. This medicine does not work against this type of infection.

Liver Dysfunction and Poor Nutritional State

Patients with abnormal liver functioning and poor nutritional state are at increased risk when using this medicine. Such patients may have an increased risk of fall in prothrombin time. Monitor prothrombin time carefully and take vitamin K as indicated by your doctor.

Interactions with Maxime

When two or more medicines are taken together, it can change how the medicines work and increase the risk of side-effects. In medical terms, this is called as a Drug Interaction.
This page does not contain all the possible interactions of Maxime Tablet. Share a list of all medicines that you use with your doctor and pharmacist. Do not start, stop, or change the dose of any medicines without the approval of your doctor.

Ketone Identification Test

Maxime Tablet interacts with a test for ketone identification in urine using nitroprusside. A false-positive result for the presence of ketones in the urine may occur.

Anticoagulants

There may be an interaction of Maxime with warfarin, which is used to prevent blood clotting. When Maxime is taken with blood thinners, it increases blood clotting time. An increased blood clotting time may indicate a higher risk of bleeding.

Anticonvulsants

Maxime Tablet may interact with carbamazepine, which is used in the treatment of seizures. When using Maxime with carbamazepine, the level and effects of carbamazepine may increase in the body.

Coombs Test

Your doctor's guidelines may need to be followed while taking this medicine along with Coombs test, which is used to determine the presence of hemolytic anemia (abnormal breakdown of red blood cells). Wrong results for the Coombs test can occur when using this medicine.

Glucose Detection Test

Special instructions need to be followed while taking this medicine along with a test for presence of glucose in the urine using Benedict’s solution or Fehling’s solution. A false-positive reaction for glucose present in the urine may occur. It is recommended that glucose tests based on enzymatic glucose oxidase reactions should be used.

Traveling With Medication

  • Ensure that you carry enough doses of each of your prescription medicines to last the entire trip. The best place to store your medicines is in the carry on baggage. However, while flying, if carrying liquid medicines, make sure you do not go over the limits imposed for carry-on liquids.
  • While traveling overseas, make sure that you can carry each of your prescription medicines legally to your destination country. One way to ensure this is by checking with your destination country's embassy or website.
  • Make sure that you carry each of your medicines in their original packaging, which should typically include your name and address, and the details of the prescribing doctor.
  • If your travel involves crossing time zones, and you are required to take your medicine as per a fixed schedule, make sure that you adjust for the change in time.

Expired Medication

Taking a single dose of expired Maxime is unlikely to cause a side-effect. However, please discuss with your doctor or pharmacist, if you feel unwell or sick. An expired medicine may become ineffective in treating your prescribed conditions. To be on the safe side, it is important not to use an expired drug. You are much safer by always keeping a fresh supply of unexpired medicines.

Safe Disposal of Medication

  • If there are disposal instructions on the package, please follow the instructions.
  • If there are medicine take-back programs in your country, you should contact the respective authority to arrange for the disposal of the medicine. For example, in the USA, the Drug Enforcement Administration regularly hosts National Prescription Drug Take-Back events.
  • If there are no take-back programs, mix the medicine with dirt and place them in a sealed plastic bag. Throw the plastic bag in your household trash. Separately, remove all personal information including the prescription label from the medicine packaging and then dispose off the container.
  • If specifically indicated on the medicine package that it needs to be flushed down the toilet when no longer needed, perform the required step.
This page provides information for Maxime Tablet .
Urinary Tract Infections
Ear Infections
Streptococcal Infections
Gonorrhea

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