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Why it's used

Clotrimazole is used to treat the fungal infection of the mouth. This medicine works by blocking the synthesis of a substance in the cell membranes of fungi. It may lead to functional and structural dysfunction of fungi. Clotrimazole is also used to reduce the incidence of fungal infection of the mouth in patients with reduced body immunity due to the treatment of blood cancer, kidney transplantation, or solid tumors by radiotherapy, chemotherapy, or steroid therapy.
When not to use
Clotrimazole should not be used to treat fungal infections affecting internal organs.
Clotrimazole is a prescription medicine that belongs to a class of medicines called Antifungal. Antifungals are a group of drugs that treat fungal infections of the skin and body, including athlete's foot, fungal nail infections, ringworm, and vaginal candidiasis. These medicines limit the growth of a wide range of fungi by damaging the fungal cell membrane.

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How to use

Follow directions on the product label, information guide, and provided by your doctor before using Clotrimazole. Eat this medicine as per your doctor's instructions.

Typical Dosage

The typical adult dose of Clotrimazole is 10 mg five times a day for continuously 14 days. The typical dose for children is 10 mg five times a day for continuously 14 days. This medicine is commonly used for a period of 14 days for fungal infection of the mouth. Clotrimazole is typically used at the same time every day. There are no known habit-forming tendencies with this medicine.

Talk to Your Doctor

Tell your doctor if your condition worsens. Talk to your doctor if nausea, unpleasant mouth sensations, vomiting, and itching.

Use in Children

If you are giving Clotrimazole to a child, be sure to use a product that is meant for use in children. Before giving this medicine, use the child's weight or age to find the right dose from the leaflet or product package. You can also read the dosage section of this page to know the correct dose for your child. Else, consult with your doctor and follow their recommendation.


Store Clotrimazole below 30ºC (86ºF), avoid freezing, and away from moisture. Keep this medicine away from children and pets.
Medicines may be given for uses other than those listed in the medicine guide. Do not use Clotrimazole for symptoms for which it was not prescribed. Do not give Clotrimazole to others who may have similar symptoms as you. Self-medication can cause harm.

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How to take Clotrimazole

Your dose may depend on several personal factors. You should consult with your doctor to find out the dose that is best for you. The dose of Clotrimazole depends on the following factors:

Clotrimazole Dosage

Dosage for fungal infection of the mouth

  • Recommended: 10 mg five times a day for continuously 14 days
Children (aged more than 3 years)
  • Recommended: 10 mg five times a day for continuously 14 days

Dosage for prevention of the fungal mouth infection

Adult (patients with reduced body immunity)
  • Recommended: 10 mg three times a day

Minimum Age

3 years

Dosage calculation for children

To calculate the dosage for children please use the weight based dose calculator to calculate the appropriate dosage as per the weight of your child.


Strength: 1 mg/100 mg, 1 mg/1 mg, 5 mg/100 mg, 2 mg/100 mg, 0.01 mg/1 mg, 6 mg/1 ml, 50 mg, 10 mg, 10 mg/1 ml, 0.01 mg/10000 mg, 1.1 mg/115 mg, 1 mg/10000 mg, 1%, 2%, and 10%
Topical Solution
Strength: 10 mg/1 ml, 1000 mg/1 ml, 1 mg/1 ml, and 10 mg
Strength: 10 mg
Aerosol, foam
Strength: 1 mg/100 mg
Aerosol, spray
Strength: 1 ml/100 ml
Strength: 1 mg/100 mg
Strength: 1 mg/1 ml, 1000 mg/100 ml, 1 mg/100 mg, 1 mg/100 ml, 10 mg/1 ml, and 10 mg

Special Instructions

Liver dysfunction
Periodic evaluation of the liver function is advised especially in patients with existing liver dysfunction.

Missed Dose

Take the missed dose as soon as you remember it. Skip the missed dose if it's time for the next dose and continue your usual dosing schedule. Avoid taking a double dose to make up for the missed dose.


What to do if you overdose on Clotrimazole?
If this happens, immediately call the emergency helpline number.
Symptoms of an overdose of Clotrimazole
If you use too much of this medicine, it could lead to dangerous levels of the medicine in your body. In such cases, symptoms of an overdose may include:
If you think you have overdosed on Clotrimazole, call a poison control center immediately. You can look up the poison control center information from the Poison Center Finder at

Precautions while using Clotrimazole

Before you use Clotrimazole, tell your doctor of your medical and health history including the following:
This medicine may cause elevated liver enzyme (SGOT) levels and abnormal liver function test.
Before you use Clotrimazole, tell your doctor if you are allergic to it or its ingredients. Your doctor may prescribe an alternative medicine and update your medical records to record this information.
The use of Clotrimazole may change liver enzyme levels. This medicine may cause elevated liver enzyme (SGOT) levels and abnormal liver function test. Periodic evaluation of the liver function is advised especially in patients with existing liver dysfunction.

Use when Pregnant

Clotrimazole should be used only when required in patients who are pregnant or planning to become pregnant. The pregnant women can use Clotrimazole only if the possible benefit outweighs the potential risk to the unborn baby.

If Breastfeeding

Consult with your doctor on the use of Clotrimazole during breastfeeding.

If trying to Conceive

Consult with your doctor on the use of Clotrimazole, if you are trying to conceive.

Clotrimazole Side-effects

Rarely, the use of Clotrimazole may cause the following side-effects:
The following severe side-effects may also occur when using Clotrimazole:
  • Liver disorder
    Symptoms: elevated liver enzyme (SGOT) level abnormal liver function tests
    Periodic evaluation of the liver function is advised especially in patients with existing liver dysfunction.
  • Vomiting
    If this happens, contact your doctor.
Your doctor has prescribed this Clotrimazole because they have judged that the benefits outweigh the risks posed by side-effects. Many people using this medicine do not have serious side-effects. This is not a complete list of possible side-effects for Clotrimazole.
If you experience side-effects or notice other side-effects not listed above, contact your doctor for medical advice. You may also report side-effects to your local food and drug administration authority. You can look up the drug authority contact information from the Drug Authority Finder at


Fungal Infections Affecting Internal Organs

Patients with fungal infections affecting internal organs (systemic mycoses including systemic candidiasis) are at increased risk when using this medicine. This medicine should not be used to treat systemic fungal infections.

Interactions with Clotrimazole

When two or more medicines are taken together, it can change how the medicines work and increase the risk of side-effects. In medical terms, this is called as a Drug Interaction.
This page does not contain all the possible interactions of Clotrimazole. Share a list of all medicines that you use with your doctor and pharmacist. Do not start, stop, or change the dose of any medicines without the approval of your doctor.

Traveling With Medication

  • Ensure that you carry enough doses of each of your prescription medicines to last the entire trip. The best place to store your medicines is in the carry on baggage. However, while flying, if carrying liquid medicines, make sure you do not go over the limits imposed for carry-on liquids.
  • While traveling overseas, make sure that you can carry each of your prescription medicines legally to your destination country. One way to ensure this is by checking with your destination country's embassy or website.
  • Make sure that you carry each of your medicines in their original packaging, which should typically include your name and address, and the details of the prescribing doctor.
  • If your travel involves crossing time zones, and you are required to take your medicine as per a fixed schedule, make sure that you adjust for the change in time.

Expired Medication

Taking a single dose of expired Clotrimazole is unlikely to cause a side-effect. However, please discuss with your doctor or pharmacist, if you feel unwell or sick. An expired medicine may become ineffective in treating your prescribed conditions. To be on the safe side, it is important not to use an expired drug. You are much safer by always keeping a fresh supply of unexpired medicines.

Safe Disposal of Medication

  • If there are disposal instructions on the package, please follow the instructions.
  • If there are medicine take-back programs in your country, you should contact the respective authority to arrange for the disposal of the medicine. For example, in the USA, the Drug Enforcement Administration regularly hosts National Prescription Drug Take-Back events.
  • If there are no take-back programs, mix the medicine with dirt and place them in a sealed plastic bag. Throw the plastic bag in your household trash. Separately, remove all personal information including the prescription label from the medicine packaging and then dispose off the container.
  • If specifically indicated on the medicine package that it needs to be flushed down the toilet when no longer needed, perform the required step.
This page provides information for Clotrimazole .
Fungal Infections
Vaginal Diseases
Vulvar Disorders
Ear Infections

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