Patients using this medicine are at increased risk. These patients may suffer from severe bleeding
k dependent bleeding disorder. The patient should be monitored for the occurrence of a bleeding disorder. If required the supplements of vitamin k should be considered.
Patients with seizure
), slow acetylator status, history of numb or weak in your arms and legs (peripheral neuropathy), psychosis
dependence or a rare blood problem (porphyria
) are at increased risk when using this medicine. These patients should be carefully monitored.
Patients who use alcohol
, being a Hispanic or black woman and patients with severe liver disease or using drugs into the vein are at increased risk when using this medicine. These patients may suffer from liver disorders. In such cases, low dose of rifampicin should be used. Patients should be observed weekly for two weeks, later every two weeks for the following six weeks during this treatment and should be questioned about the symptoms related to side effects. The level of liver enzymes, bilirubin, blood creatinine
, and a complete blood count should also be monitored. Stop using rifampicin if symptoms of liver damage occur.
Patients with genetic problems including fructose intolerance, decreased absorption of glucose-galactose, and sucrase-isomaltase insufficiency are at increased risk when using this medicine. These patients should not use this medicine.
High Levels of Bilirubin in the Blood
Patients using this medicine are at increased risk. This medicine may cause increased blood bilirubin level.
Severe Skin Reaction
Patients using this medicine are at increased risk. These patients may suffer from severe skin allergic reactions, that can be life-threatening or possibly fatal. Symptoms such as fever
, abnormalities of lymph nodes or liver abnormalities may be present in such patients. The patient is advised to monitor closely for the symptoms of skin reactions. If the symptoms are present, then the treatment with this medicine should be stopped and consult your doctor immediately. An alternative treatment should be considered.
Worsening of Blood Disorder
Patients using this medicine are at increased risk. The use of this medicine may cause worsening of blood disorder and discoloration of the teeth, sweat
, urine, sputum, and tears
. This medicine may permanently stain soft contact lenses.