Before you use
Lansoprazole, tell your doctor if you are allergic to it or its ingredients. Your doctor may prescribe an alternative medicine and update your medical records to record this information.
Before you use
Lansoprazole, tell your doctor of your medical history including
liver problems, abnormal functioning of the
liver, patients allergic to
Lansoprazole or similar medicine that decreases stomach acid, stomach, intestine or duodenal
ulcer, low levels of
magnesium in the blood,
phenylalanine build-up in the body (
phenylketonuria), planning to have blood test of Chromogranin A, patients taking
corticosteroids, weak or brittle joint (
osteoporosis), patients taking
digoxin,
itraconazole,
iron salts,
methotrexate, St John´s wort,
ampicillin,
ketoconazole,
rifampicin,
theophylline,
atanazavir,
warfarin,
fluoxamine, methotrexate,
rilpivirine, or
sucralfate, low levels of
vitamin B-12 in your body, or an autoimmune disease (condition in which the body attacks its own organs, causing swelling and loss of function) such as systemic
lupus erythematosus. Using
Lansoprazole in patients with liver problems or abnormal functioning of the liver may increase the exposure of this medicine. Patients with stomach, intestine or duodenal ulcer are at increased risk of stomach ulcer due to the presence of bacteria (Helicobacter pylori) when using
Lansoprazole. Patients allergic to similar medicines that reduce stomach acid may experience skin rash or
pain in joints. Patients with a history of weak or brittle joints (
osteoporosis) are at increased risk of
fracture in the hip, spine or wrist when using Lansoprazole. Patients with low magnesium levels in the blood may experience
seizures, abnormal or fast heartbeat,
dizziness, muscle weakness,
cramps or muscle aches, nervousness (jitteriness), spasms of the hands and feet, spasm of the voice box when using Lansoprazole. Using Lansoprazole with
digoxin, ampicillin esters, ketoconazole,
iron salts may decrease the absorption of these medicines. Using Lansoprazole with
rifampicin and St John´s wort decreases the absorption of Lansoprazole. Using Lansoprazole with
theophylline increase the clearance of theophylline. Using Lansoprazole with
atazanavir may decrease the effectiveness of atazanavir. Using Lansoprazole with warfarin may increase the prothrombin time and risk of stomach and intestinal disorders. Using Lansoprazole with
fluvoxamine may increase the level of Lansoprazole. The use of sucralfate may decrease the absorption of Lansoprazole in the blood. The use of Lansoprazole with methotrexate may increase the level of methotrexate in the blood.
The use of this medicine may change magnesium. Magnesium levels should be checked before starting the treatment because low levels of magnesium can happen in individuals who take a proton pump inhibitor medicine for at least three months.
The use of Lansoprazole may change blood clotting parameter. Using Lansoprazole with warfarin increases the blood clotting parameter (International Normalized Ratio (INR) and prothrombin time), which may lead to abnormal
bleeding and fatal. Patients should be monitored for the blood clotting parameters.
The use of this medicine may change liver parameters (such as aspartate transaminase (SGOT or AST), alanine transaminase (SGPT or ALT), gamma-glutamyl transferase (GGTP),
creatinine, bilirubin, alkaline phosphatase). Increase in the level of aspartate transaminase (SGOT or AST), alanine transaminase (SGPT or ALT), gamma-glutamyl transferase (GGTP), bilirubin, creatinine, and alkaline phosphatase may be observed in patients taking Lansoprazole.
The use of this medicine may change blood parameters (such as white blood cells (WBC),
globulin, albumin to globulin ratio (A/G ratio), red blood cells (RBC), blood
potassium, blood urea, hemoglobin,
lipid,
cholestrol, electrolytes,
glucocorticoids, Lactate dehydrogenase (LDH),
platelets). Increase or decrease or abnormal levels of white blood cells, increase in potassium, increase in blood urea, decrease in hemoglobin, increase in lipid (
hyperlipemia), increase in cholesterol, increase or decrease electrolyte, increase glucocorticoids, increase in lactate dehydrogenase (LDH), increase or decrease or abnormal platelets levels may be observed in patients taking Lansoprazole therapy.
The use of Lansoprazole may change urine parameters (such as
crystal urea, albuminuria,
glycosuria, hematuria). Increase in the levels of crystals in the urine (crystal urea), albumin in urine (albuminuria), glucose in urine (glycosuria), blood in the urine (hematuria) may be observed in patients taking Lansoprazole therapy.
Lansoprazole should be used in
pregnancy only when required. There are no sufficient clinical data available in pregnant women. Lansoprazole should be used during
pregnancy only after considering the
importance of the drug to mother. Lansoprazole should be used while
breastfeeding only when required. It is unknown whether Lansoprazole may pass into breast milk which may cause harmful effects in children. A decision to discontinue Lansoprazole or
breastfeeding should be made after considering the importance of medicine to the mother. It is not known if this medicine is safe for use in women who are conceiving. Consult with your doctor before you use Lansoprazole. It is unknown whether Lansoprazole may harm the unborn baby.
Lansoprazole can make you feel sleepy. Be careful while driving, using machinery, or doing any other activity that needs you to be alert. The consumption of
alcohol with Lansoprazole can make you feel more sleepy. Lansoprazole may cause
seizures in some people. Discuss with your doctor if you perform activities where a loss of consciousness may cause you or others harm.
This medicine can cause stomach
bleeding. The use of alcohol/tobacco with
Lansoprazole may increase your stomach bleeding risk. If you drink
alcohol or smoke regularly, please discuss with your doctor. This medicine may increase your sensitivity to sunlight. If this happens, limit your time outdoors and do not tan to prevent
sunburns. Cover your skin when you are outdoors or use a sunscreen. In case you get a sunburn, consult with your doctor.
Lansoprazole may increase
side-effects in older patients. Elderly patients may see an increased risk of
fracture of the hip, fracture of the wrist, and spine fracture.
Using Lansoprazole for long-term (more than one year) or at high doses may increase the risk of
fracture in the hip, wrist or spine due to the weak or brittle joint (osteoporosis-related fractures) and decrease the level of magnesium in the blood.