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    What is Metformin?

    Metformin is used for Type 2 diabetes mellitus, Maturity onset diabetes, Polycystic ovary syndrome, Type 2 diabetes, Polycystic ovarian syndrome and other conditions. This salt may also be used for purposes not listed in this medication guide. Detailed information related to Metformin's uses, side-effects, reviews, questions, interactions, and precautions is as follows:

    Metformin Uses

    Metformin is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms:
    References: 1
    Learn more: Uses

    Metformin - Side-effects

    The following is a list of possible side-effects that may occur in medicines that contain Metformin. This is not a comprehensive list. These side-effects are possible, but do not always occur. Some of the side-effects may be rare but serious. Consult your doctor if you observe any of the following side-effects, especially if they do not go away.
    If you notice other side-effects not listed above, contact your doctor for medical advice. You may also report side-effects to your local food and drug administration authority.
    References: 2
    Learn more: Side-effects

    Metformin Working, Mechanism of Action and Pharmacology

    Metformin improves the patient's condition by performing the following functions:
    References: 3

    Metformin - Precautions & How to Use

    Before using Metformin, inform your doctor about your current list of medications, over the counter products (e.g. vitamins, herbal supplements, etc.), allergies, pre-existing diseases, and current health conditions (e.g. pregnancy, upcoming surgery, etc.). Some health conditions may make you more susceptible to the side-effects of the drug. Take as directed by your doctor or follow the direction printed on the product insert. Dosage is based on your condition. Tell your doctor if your condition persists or worsens. Important counseling points are listed below.
    • Blurred vision
    • Diabetic ketoacidosis
    • Symptoms like nausea, vomiting, abdominal pain, fatigue, anorexia and dark urine

    Metformin - Drug Interactions

    If you use other drugs or over the counter products at the same time, the effects of Metformin may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Metformin may interact with the following drugs and products:
    Learn more: Interactions

    Metformin - Contraindications

    Hypersensitivity to Metformin is a contraindication. In addition, Metformin should not be used if you have the following conditions:
    Learn more: Contraindications

    Metformin - Frequently asked Questions

    • Is Metformin safe to consume or apply when pregnant?
      Please consult with your doctor for case-specific recommendations.
    • Is Metformin safe while breastfeeding?
      Please discuss the risks and benefits with your doctor.
    • Can Metformin be used for type 2 diabetes mellitus and maturity onset diabetes?
      Yes, type 2 diabetes mellitus and maturity onset diabetes are among the most common reported uses for Metformin. Please do not use Metformin for type 2 diabetes mellitus and maturity onset diabetes without consulting first with your doctor. Click here and view survey results to find out what other patients report as common uses for Metformin.
    • How long do I need to use Metformin before I see improvement of my conditions?
      TabletWise.com website users have reported 2 weeks and 1 month as the most common time it takes before they saw improvements in their conditions. These times may not be reflective of what you may experience or how you should use this medicine. Please consult with your doctor to check how long do you need to use Metformin. Click here and view survey results to find out what other patients report as time for effectiveness for Metformin.
    • At what frequency do I need to use Metformin?
      TabletWise.com website users have reported twice a day and once a day as the most common frequency of using Metformin. Please follow your doctor's advice on how often you need to Metformin. Click here and view survey results to find out what other patients report as frequency of using Metformin.
    • Should I consume Metformin empty stomach, before food or after food?
      TabletWise.com website users have most commonly reported consuming Metformin after food. However, this may not be reflective of how you should consume this medicine. Please follow your doctor's advice on how you should use this medicine. Click here and view survey results to find out what other patients report as timing of using Metformin.
    • Is it safe to drive or operate heavy machinery when consuming?
      If you experience drowsiness, dizziness, hypotension or a headache as side-effects when using Metformin medicine then it may not be safe to drive a vehicle or operate heavy machinery. One should not drive a vehicle if using the medicine makes you drowsy, dizzy or lowers your blood-pressure extensively. Pharmacists also advise patients not to drink alcohol with medicines as alcohol intensifies drowsiness side-effects. Please check for these effects on your body when using Metformin. Always consult with your doctor for recommendations specific to your body and health conditions.
    • Is this medicine or product addictive or habit forming?
      Most medicines don't come with a potential for addiction or abuse. Usually, government's categorizes medicines that can be addictive as controlled substances. Examples include schedule H or X in India and schedule II-V in the US. Please consult the product package to make sure that the medicine does not belong to such special categorizations of medicines. Lastly, do not self-medicate and increase your body's dependence to medicines without the advice of a doctor.
    • Can it be stopped immediately or do I have to slowly ween off consumption?
      Some medicines need to be tapered or cannot be stopped immediately because of rebound effects. Please consult with your doctor for recommendations specific to your body, health and other medications that you may be using.

    Other important Information on Metformin

    Missing a dose

    In case you miss a dose, use it as soon as you notice. If it is close to the time of your next dose, skip the missed dose and resume your dosing schedule. Do not use extra dose to make up for a missed dose. If you are regularly missing doses, consider setting an alarm or asking a family member to remind you. Please consult your doctor to discuss changes in your dosing schedule or a new schedule to make up for missed doses, if you have missed too many doses recently.
    References: 4, 5, 6, 7

    Overdosage of Metformin

    • Do not use more than prescribed dose. Taking more medication will not improve your symptoms; rather they may cause poisoning or serious side-effects. If you suspect that you or anyone else who may have overdosed of Metformin, please go to the emergency department of the closest hospital or nursing home. Bring a medicine box, container, or label with you to help doctors with necessary information.
    • Do not give your medicines to other people even if you know that they have the same condition or it seems that they may have similar conditions. This may lead to overdosage.
    • Please consult your physician or pharmacist or product package for more information.
    References: 8, 9, 10

    Storage of Metformin

    • Store medicines at room temperature, away from heat and direct light. Do not freeze medicines unless required by package insert. Keep medicines away from children and pets.
    • Do not flush medications down the toilet or pour them into drainage unless instructed to do so. Medication discarded in this manner may contaminate the environment. Please consult your pharmacist or doctor for more details on how to safely discard Metformin.
    References: 11, 12, 13, 14

    Expired Metformin

    • Taking a single dose of expired Metformin is unlikely to produce an adverse event. However, please discuss with your primary health provider or pharmacist for proper advice or if you feel unwell or sick. Expired drug may become ineffective in treating your prescribed conditions. To be on the safe side, it is important not to use expired drug. If you have a chronic illness that requires taking medicine constantly such as heart condition, seizures, and life-threatening allergies, you are much safer keeping in touch with your primary health care provider so that you can have a fresh supply of unexpired medications.
    References: 15, 16

    Dosage Information

    Please consult your physician or pharmacist or refer to product package.

    References

    1. Maruthur, NM; Tseng, E; Hutfless, S; Wilson, LM; Suarez-Cuervo, C; Berger, Z; Chu, Y; Iyoha, E; Segal, JB; Bolen, S (19 April 2016). "Diabetes Medications as Monotherapy or Metformin-Based Combination Therapy for Type 2 Diabetes: A Systematic Review and Meta-analysis.". Annals of Internal Medicine. doi:10.7326/M15-2650. https://dx.doi.org/10.7326%2FM15-2650 - Accessed: October 12, 2016.
    2. Bolen S, Feldman L, Vassy J, et al. Systematic review: comparative effectiveness and safety of oral medications for type 2 diabetes mellitus. Ann Intern Med. 2007;147(6):386_99. doi:10.7326/0003-4819-147-6-200709180-00178. PMID 17638715. https://www.ncbi.nlm.nih.gov/pubmed/1763... - Accessed: October 12, 2016.
    3. Kirpichnikov D, McFarlane SI, Sowers JR. Metformin: an update [PDF]. Ann Intern Med. 2002;137(1):25_33. doi:10.7326/0003-4819-137-1-200207020-00009. PMID 12093242. http://annals.org/article.aspx?articleid... - Accessed: October 12, 2016.
    4. NHS Choices. What should I do if I miss a dose of antibiotics? - Accessed: July 14, 2016.
    5. Ever Miss a Dose of Your Medicine? - Accessed: July 3, 2016.
    6. Cancer.Net (2014). The Importance of Taking Your Medication Correctly - Accessed: July 3, 2016.
    7. Schachter, S.C., Shafer, P. O. &; Sirven, J.I. (2013). Missed Medicines. Epilepsy Foundation - Accessed: May 28, 2016.
    8. National Institute of Drug Abuse (2010). Prescription Drugs: Abuse and Addiction. Report Research Series - Accessed: July 21, 2016.
    9. eMedicinehealth (2016). Drug Overdose Overview - Accessed: July 21, 2016.
    10. Centers for Disease Control and Prevention (2010). Unintentional drug poisoning in the United States - Accessed: July 21, 2016.
    11. Centers for Disease Control and Prevention. December 12, 2011. Put your medicines up and away and out of sight - Accessed: June 10, 2016.
    12. The Center for Improving Medication Management and the National Council on Patient Information and Education. The quick scoop: medicines and your family: safely storing and disposing of medicines - Accessed: June 10, 2016.
    13. U.S. Food and Drug Administration. December 24, 2013. How to dispose of unused medications - Accessed: June 10, 2016.
    14. World Health Organization: Information sheet: Pharmaceuticals in drinking-water - Accessed: July 1, 2016.
    15. Lyon, R. C., Taylor, J. S., Porter, D. A., et al. (2006) Stability profiles of drug products extended beyond labeled expiration dates. Journal of Pharmaceutical Sciences; 95:1549-60 - Accessed: July 3, 2016.
    16. Harvard Medical School (2016). Drug Expiration Dates - Do They Mean Anything? - Accessed: May 1, 2016.

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    Last updated date

    This page was last updated on 8/06/2018.
    This page provides information for Metformin in English.
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