Interference with Serological Testing
Use of Oframax may lead to false positive results for the determination of glucose in urine. An alternative testing method should be followed to avoid false positive results.
Allergy to Oframax
Patients who are allergic to Oframax are at an increased risk. Such patients may see an increased risk of life-threatening allergic reactions such as Stevens-Johnson
syndrome or Lyell's syndrome. These patients should discontinue the use of this medicine.
Abnormal Functioning of the Liver and Kidneys
Such patients are at an increased risk when using this medicine. Careful clinical monitoring of
safety and efficacy data is advisable for Oframax.
Kidney Problems
Patients with a history of kidney stone and excessive urinary
calcium excretion are at an increased risk when using this medicine. In such patients, the kidney stone may occur upon discontinuation of Oframax.
Treatment With Oframax
Patients treated with this medicine are at an increased risk of inflammation of the pancreas (
pancreatitis).
Use of Oframax Sodium
Patients, who use Oframax
sodium are at increased risk. Such patients should follow a controlled sodium
diet.
Long-Term Treatment with Oframax
Patients on long-term treatment with cephalosporins are at an increased risk when using this medicine. In such patients, complete blood count should be checked regularly.
Use of Antibacterial Medicines
Patients who use antibacterial medicines including Oframax are at increased risk. In such patients, severe
diarrhea may occur which is caused by Clostridium difficile bacteria. If this happens, stop using this medicine and take protein supplements or maintain the
balance of body fluid and electrolyte (example
sodium, chloride,
potassium, and bicarbonate).
Hemolytic Anemia
Patients receiving cephalosporins are at an increased risk of abnormal breakdown of red blood cells (hemolytic
anemia). Such patients may see an increased risk of fatal conditions both in adults and children. If this happens, stop using this medicine until its cause is determined.
Interaction with Calcium-Containing Solution
Patients, who use calcium-containing solution to prepare the injection are at high risk. When the injection of this medicine is prepared with calcium-containing solutions, then it may lead to an increased risk of formation of solid
calcium particles. Do not use calcium-containing solutions (such as Ringer’s solution or Hartmann’s solution) for preparing the injection.