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    Does Gas x make you fart?

     
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    Gas-X is a brand name drug from GlaskoSmithKline. It is used to provide relief of pressure, bloating, and fullness commonly referred to as gas. The active ingredient responsible for how the drug works is simethicone. Simethicone is an anti-foaming agent that is marketed to reduce the buildup of intestinal gases that cause bloating and discomforting i.e. farting. It does this by reducing the surface tension of gas bubbles causing them to break apart and pass more smoothly through your body.
    
    In theory, the action on surface tension should actually prevent or stop farting, not cause it. However, there are only a few randomized controlled trials with simethicone that show inconsistent results for gas relief. Other methods to manage gas include dietary changes, enzyme preparations to facilitate digestion, adsorbents, treatments to change gut flora, and drugs that modify gut transit.
    
    References
    1. GlaskoSmithKline Gas-X Usage Accessed February 24, 2018.
    3. Hasler WL. Gas and Bloating. Gastroenterol Hepatol (N Y). 2006;2(9):654-662 URL: https://www.ncbi.nlm.nih.gov/pubmed/28316536 Accessed February 24, 2018
    4. Holtmann G, Gschossmann J, Karaus M, et al. Randomised double-blind comparison of simethicone with cisapride in functional dyspepsia. Aliment Pharmacol Ther. 1999;13:1459-1465 URL: https://www.ncbi.nlm.nih.gov/pubmed/10571602 Accessed February 24, 2018
    5. Kaplan MA, Prior MJ, Ash RR, et al. Loperamide-simethicone vs loperamide alone, simethicone alone, and placebo in the treatment of acute diarrhea with gas-related abdominal discomfort. A randomized controlled trial. Arch Fam Med. 1999;8:243-248 URL: https://www.ncbi.nlm.nih.gov/pubmed/10333820 Accessed February 24, 2018 Accessed February 24, 2018
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