Read the directions on the product label, patient guide, or
medicine guide provided by the medicine company or your pharmacist before starting to use
Negazole Tablet. If you have any questions related to this medicine, ask your doctor or pharmacist. Use this medicine as recommended by your doctor.
Negazole Tablet is used with or after food. Negazole should be swallowed with water. It should not be chewed.
The typical dose of Negazole is 750 mg three times daily orally for 5 to 10 days. The usual dose for children is 35 to 50 mg/kg/24 hours or 15.9 to 22.7 mg/lb/kg/24 hours, orally for 10 days divided into three doses. The maximum adult dose of
Negazole is 2000 mg in a day. This medicine is typically used for a period of 7 days for
trichomoniasis, 5-10 days for amebiasis, 7-10 days for anaerobic bacterial infections, 5-7 days for bacterial
vaginosis, 3-10 days for
giardiasis, 3 days for acute ulcerative
gingivitis, 3-7 days for acute dental infections, 7 days for leg
ulcers and pressure sores, and 7-14 days for eradication of Helicobacter pylori.
This medicine should be used on an
as-needed basis. Infections of the bone and joint, endocardium, and lower respiratory tract may require longer treatment. You should continue to use this medicine as directed by the doctor even if you feel well.
Talk to your doctor if your condition does not improve or worsens. Tell your doctor if stomach
pain, abnormally low weight,
nausea, vomiting,
fever, feeling of discomfort,
fatigue, yellowing of the skin, dark urine, and discolored
stools or
itching. If you have issues with the health of your liver, For patients with severe liver damage (Child-Pugh C), the dose of Negazole should be reduced by 50%.
Your doctor may recommend a lower initial dose of this
medicine to see the impact of this medicine on the body. Please follow your doctor's directions. Older patients may see an increase in the incidence of
side-effects with this medicine. As a result, a lower dose may be recommended for older patients.
If you are giving
Negazole Tablet to a child, be sure to use a product that is meant for children. Before giving this medicine to a child, use the child's weight or age to find the right dose from the product package. You can also read the
dosage section of this page to know the correct dose for your child. Else, consult with your doctor and follow their recommendation.
To decrease the possibility of side-effects, you might be recommended to use the extended-release form of this
medicine by your doctor. The extended-release medicine helps in maintaining a steady level of the medicine in your body for a longer period of time. Do not crush or chew the medicine, unless indicated on the package or by your doctor.
Negazole is intended for intravenous (into the veins) use only. Negazole is to be given slowly by intravenous drip infusion only, either as a constant or periodic infusion. Intravenous admixtures comprising Negazole and other drugs should be avoided. Negazole Injection, USP is a ready-to-use isotonic solution. There is no requirement of dilution or buffering and do not refrigerate the injection.
Avoid the consumption of
alcohol with Negazole.
Your doctor may request that specific lab tests be performed before you start using
Negazole Tablet. You may need to have
Antibiotic Susceptibility test. This test helps the doctor in selecting an appropriate antibacterial drug for starting the therapy. Your doctor may request liver function test test. Liver function tests must be done just before to the start of treatment, throughout and after the end of treatment until liver function is within average ranges, or till the baseline values are achieved. Negazole should be discontinued if the liver function tests become markedly raised during treatment.
You should store
Negazole Tablet below 25°C (77°F), away from excess heat and moisture, and protect from light. Store the
medicine away from the reach of children and
pets.
Medicines may be prescribed for uses other than those listed in the medicine guide. Do not use
Negazole Tablet for conditions for which it was not prescribed. Do not give Negazole Tablet to other people who might have the same conditions or symptoms that you have. Self-medication may harm them.