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Why it's used

Opizole Cream is used to treat all fungal skin infections such as infection of the vulva and also used with other medicines to treat infection of the vagina. It is also used to prevent reinfection by applying on the penis of the sexual partner. Opizole solution can also be used to treat fungal infections of the middle ear and outer ear. This medicine works by blocking the synthesis of a substance in the cell membranes of fungi. It may lead to functional and structural dysfunction of fungi.
Antifungal
Opizole belongs to the Antifungal class of medicines. Antifungals are a group of drugs that treat fungal infections of the skin and body, including athlete's foot, fungal nail infections, ringworm, and vaginal candidiasis. These medicines limit the growth of a wide range of fungi by damaging the fungal cell membrane.

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How to use

Read the directions on the product label, patient guide, or medicine guide provided by the medicine company or your pharmacist before starting to use Opizole Cream. If you have any questions related to this medicine, ask your doctor or pharmacist. Apply this medicine as recommended by your doctor.

Typical Dosage

Opizole is commonly used at the same time every day. This medicine is not known to be habit-forming.

Talk to Your Doctor

Talk to your doctor if your condition persists or worsens or if you develop new symptoms. Tell your doctor if skin rash, swallowing problems, breathing problems, swelling of the lips, swelling of the face, swelling of the throat, swelling of the tongue, weakness, feeling dizzy, feeling faint, nausea, redness of the skin, burning of the skin, pain on the affected area, itching of the skin, swelling of the skin, blisters, discomfort, irritation, peeling of the skin, hives, stomach pain, fever, chills, vomiting, and abnormal vaginal discharge.

Use in Children

If you are giving Opizole Cream to a child, be sure to use a product that is meant for children. Before giving this medicine to a child, use the child's weight or age to find the right dose from the product package. If the product package does not provide specific information as to how the medicine can be given to children, consult with your doctor and follow their recommendation.

Storage

You should store Opizole Cream below or at 25ºC (77ºF) for 10 g tube and solution of Opizole. The 20 g tube does not require any specific storage conditions. Store the medicine away from the reach of children and pets.
Medicines may be prescribed for uses other than those listed in the medicine guide. Do not use Opizole Cream for conditions for which it was not prescribed. Do not give Opizole Cream to other people who might have the same conditions or symptoms that you have. Self-medication may harm them.

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How to take Opizole

The dose and frequency of using Opizole will depend on the following factors:

Opizole Dosage

Dosage for Fungal infections

Adult (infection of vagina or ear)
  • Recommended: A thin layer of Opizole should be applied and gently rubbed to the affected area for 2-3 times daily.

Minimum Age

12 years

Forms

Cream
Strength: 1 mg/100 mg, 1 mg/1 mg, 5 mg/100 mg, 2 mg/100 mg, 0.01 mg/1 mg, 6 mg/1 ml, 50 mg, 10 mg, 10 mg/1 ml, 0.01 mg/10000 mg, 1.1 mg/115 mg, 1 mg/10000 mg, 1%, 2%, and 10%
Topical Solution
Strength: 10 mg/1 ml, 1000 mg/1 ml, 1 mg/1 ml, and 10 mg
Lozenge
Strength: 10 mg
Aerosol, foam
Strength: 1 mg/100 mg
Aerosol, spray
Strength: 1 ml/100 ml
Gel
Strength: 1 mg/100 mg
Liquid
Strength: 1 mg/1 ml, 1000 mg/100 ml, 1 mg/100 mg, 1 mg/100 ml, 10 mg/1 ml, and 10 mg

Overdose

What to do if you overdose on Opizole?
In case of accidental orally taken, close supervision should be provided. Stomach emptying should be performed by cleaning out the contents of the stomach if overdose symptoms occur such as dizziness, vomiting or nausea. Stomach emptying should be conducted if sufficient airway provided to the patient.
Symptoms of an overdose of Opizole
If you use too much of this medicine, it could lead to dangerous levels of the medicine in your body. In such cases, symptoms of an overdose may include:
If you think you have overdosed on Opizole Cream, call a poison control center immediately. You can look up the poison control center information from the Poison Center Finder at TabletWise.com.

Precautions while using Opizole

Before you use Opizole, tell your doctor of your medical and health history including the following:
Before using Opizole, you should see your doctor if you have these symptoms or conditions. In such cases, this medicine may not be the right treatment.
Before you use Opizole, tell your doctor if you are allergic to it or its ingredients. Your doctor may prescribe an alternative medicine and update your medical records to record this information. Discuss with your doctor if you are allergic to cetostearyl alcohol.

Use when Pregnant

Opizole should be used only when required in patients who are pregnant or planning to become pregnant. Supervision of a doctor is necessary when using this medicine in pregnant women.

If Breastfeeding

Consult with your doctor on the use of Opizole Cream during breastfeeding. This medicine may pass into breast milk. A decision should be made whether to discontinue using this medicine or to discontinue breastfeeding taking into account that the benefit of therapy for the woman and breastfeeding child.

If trying to Conceive

Consult with your doctor on the use of Opizole, if you are trying to conceive.

Dizziness

Opizole can make you feel sleepy. Be careful, especially while driving, while using heavy machinery, or when doing any activity that needs you to be completely alert. The consumption of alcohol with Opizole can worsen the sleepiness.

What precautions should be taken during Pregnancy and Nursing, and administering Opizole to Children or the Older Adults?

Pregnant Women

Only When Necessary
Warning: Supervision of a doctor is necessary when using this medicine in pregnant women.

Breastfeeding

Only When Necessary
Warning: This medicine may pass into breast milk. A decision should be made whether to discontinue using this medicine or to discontinue breastfeeding taking into account that the benefit of therapy for the woman and breastfeeding child.

Younger Adults Population

Possibly safe
Warning: There is no clinical practice for the use of Opizole cream in children. Ask a doctor to use this medicine in children under the age of 12 years.

Opizole Side-effects

Rarely, the use of Opizole Cream may cause the following side-effects:
The following severe side-effects may also occur when using Opizole Cream:
  • Skin tissue disorders
    Symptoms: swelling of the skin due to fluid accumulation, severe allergic reaction (erythema), skin rash skin burning
    If this happens, ask your doctor immediately.
  • Immune system disorders
    Symptoms: high blood pressure shortness of breath (dyspnea)
  • Severe allergic reactions
    Symptoms: swallowing problems breathing problems
    In this case, call your doctor right away.
Your doctor has prescribed Opizole Cream because they judge that the benefit is greater than the risk posed by side-effects. Many people using this medicine do not have serious side-effects. This page does not list all possible side-effects of Opizole Cream.
If you experience side-effects or notice other side-effects not listed above, contact your doctor for medical advice. You may also report side-effects to your local food and drug administration authority. You can look up the drug authority contact information from the Drug Authority Finder at TabletWise.com.

Side-effects and Allergic Reactions of Opizole by Severity and Frequency

Infrequent and Rare Side-effects

Following are the infrequent and rare side-effects of this medicine:

Severe Side-effects

Following are the severe side-effects of this medicine:

Mild Allergic Reactions

Following are the symptoms of mild allergic reactions to this medicine:
  • burning
  • feeling dizzy
  • nausea
  • pain on the affected area
  • skin itching
  • skin redness
  • swelling of your lips, face, throat or tongue
  • weakness

Serious Allergic Reactions

Following are the symptoms of serious allergic reactions to this medicine:
If this happens, stop using this medicine and contact your doctor right away.
If you experience side-effects or notice other side-effects not listed above, contact your doctor for medical advice. You may also report side-effects to your local food and drug administration authority. You can look up the drug authority contact information from the Drug Authority Finder at TabletWise.com.

Warnings

Previous Medical Conditions

If the patient had more than two fungal infections of the vagina in the previous six months and the history of a sexually transmitted disease to the patient or patient's partner, medical advice should be taken before using Opizole in such patient. Patients with pregnancy, aged under 16 years or over 60 years and allergy to vaginal antifungal medicines, should seek advice from the doctor before starting treatment.

Medical Conditions

Patients with irregular vaginal bleeding, vaginal or vulval ulcers, sores or blisters, vaginal blood-stained discharge, stomach pain, painful urination after using the Opizole, should stop the treatment and take advice from the doctor. Patients using Opizole may experience irritation, redness or swelling, fever or chills, vomiting, nausea, diarrhea or a foul smell from vaginal discharge. In such patients, the treatment should be discontinued.

Cetostearyl Alcohol

The product of Opizole contains cetostearyl alcohol, that may induce skin reactions such as red, itchy rash caused by contact with a substance (contact dermatitis).

External Use Only

These products are not for oral use. In the case of oral ingestion or eye contact, ask your doctor right away or wash it with water immediately and contact with the accident and emergency department of the nearest hospital.

Interactions with Opizole

When two or more medicines are taken together, it can change how the medicines work and increase the risk of side-effects. In medical terms, this is called as a Drug Interaction.
This page does not contain all the possible interactions of Opizole Cream. Share a list of all medicines that you use with your doctor and pharmacist. Do not start, stop, or change the dose of any medicines without the approval of your doctor.

Contraceptives

Opizole Cream may interact with contraceptives, which are used to prevent pregnancy. The use of contraceptives with Opizole may damage latex contraceptives. So, the effectiveness of contraceptives may be reduced. Contraceptives should not be used with Opizole. Patients should take alternative precautions for birth control for at least five days after using Opizole. Avoid vaginal intercourse.

Antibiotics

There may be an interaction of Opizole with sofradex, which is used to treat ear infections. The use of Opizole solution with Sofradex ear drops may cause heat reaction.

Interactions of Opizole by Severity

Severe

The following medicines are usually not to be taken together without consulting with your doctor or pharmacist.

Moderate

The following medicines may interact when taken together and can increase your risk of harmful effects. Please consult with your doctor or pharmacist before taking these medicines together.

When should Opizole be not used?

Allergy

The patients should not use Opizole if they allergic to it or any of the other ingredients, including cetostearyl alcohol.

Contraceptives

The use of contraceptives with Opizole may damage latex contraceptives. So, the effectiveness of contraceptives may be reduced. Tampons, spermicides, douches, or other vaginal products should not be used with Opizole. Patients should take alternative precautions for birth control for at least five days after using Opizole. Avoid vaginal intercourse.

Expired Medication

Taking a single dose of expired Opizole is unlikely to cause a side-effect. However, please discuss with your doctor or pharmacist, if you feel unwell or sick. An expired medicine may become ineffective in treating your prescribed conditions. To be on the safe side, it is important not to use an expired drug. You are much safer by always keeping a fresh supply of unexpired medicines.

Safe Disposal of Medication

  • If there are disposal instructions on the package, please follow the instructions.
  • If there are medicine take-back programs in your country, you should contact the respective authority to arrange for the disposal of the medicine. For example, in the USA, the Drug Enforcement Administration regularly hosts National Prescription Drug Take-Back events.
  • If there are no take-back programs, mix the medicine with dirt and place them in a sealed plastic bag. Throw the plastic bag in your household trash. Separately, remove all personal information including the prescription label from the medicine packaging and then dispose off the container.
  • If specifically indicated on the medicine package that it needs to be flushed down the toilet when no longer needed, perform the required step.
This page provides information for Opizole Cream .
Fungal Infections
Vaginal Diseases
Vulvar Disorders
Ear Infections

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