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Why it's used

Xyzal Tablet is used to relieve seasonal and year-round allergies. This medicine works by blocking certain organic substances, called histamines, in the brain and other areas of the body. Xyzal is also used to treat severe allergies due to food, medicines, or other causes. This medicine helps by treating the symptoms of the allergic reaction including skin rashes.
Xyzal belongs to a class of medicines called Antihistamines. Antihistamines help in relieving allergic symptoms. They do so by blocking the effects of histamines. Histamines are produced by the body and in-turn cause fever, itching, sneezing, a runny nose, or watery eyes in allergic conditions.

How to use

Read the directions on the product label, patient guide, or medicine guide provided by the medicine company or your pharmacist before starting to use Xyzal Tablet. If you have any questions related to this medicine, ask your doctor or pharmacist. Consume this medicine as recommended by your doctor.
Xyzal Tablet is consumed with or without food. Take this medicine as a single dose. Xyzal Tablet is consumed usually in the evening. This is because Xyzal may cause dizziness.

Typical Dosage

The typical dose of Xyzal is 5 mg once a day. The usual dose for children is 2.5 mg once a day. Xyzal is commonly used at the same time every day. It takes 1 hour for this medicine to start to work. This medicine is not known to be habit-forming.
This medicine should be used on an as-needed basis. If used for the treatment of allergies, the medicine can be stopped once the symptoms have disappeared and can be restarted again if symptoms reappear. If you experience symptoms for more than four days a week or for more than four weeks a year, your doctor may ask you to continue the treatment. Your treatment may continue as long as you are exposed to substances that cause your allergy.
If using the liquid form of this medicine, measure the dose using the provided measuring cup, spoon, or dropper. Before pouring the medicine into the measuring device, you should check the measurement markings carefully. Then, pour the dose amount into the device. After use, clean and store the measuring device in a safe place for your next use. You should not use a tablespoon or teaspoon as the dose measuring devices since it can result in an incorrect dose. If indicated on the product package, shake the medicine before use.

Talk to Your Doctor

Talk to your doctor if your condition does not improve. If you have any kidney disease, a low dose of Xyzal will usually be given.
Taking a higher dose of this medicine may increase the risk of side-effects. Older patients may see an increase in the incidence of side-effects with this medicine. As a result, a lower dose may be recommended for older patients.

Use in Children

If you are giving Xyzal Tablet to a child, be sure to use a product that is meant for children. Before giving this medicine to a child, use the child's weight or age to find the right dose from the product package. You can also read the dosage section of this page to know the correct dose for your child. Else, consult with your doctor and follow their recommendation.

Avoid Alcohol

Avoid the consumption of alcohol with Xyzal.


You should store Xyzal Tablet at 20-25°C (68-77°F). Store the medicine away from the reach of children and pets.
Medicines may be prescribed for uses other than those listed in the medicine guide. Do not use Xyzal Tablet for conditions for which it was not prescribed. Do not give Xyzal Tablet to other people who might have the same conditions or symptoms that you have. Self-medication may harm them.
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How to take Xyzal

Your dose and how often you take Xyzal will depend on the following factors:
  • age
  • weight
  • patient's health
  • the health of the patient's liver
  • medicines recommended by the doctor
  • any other medicines being used
  • herbal supplements in use

Xyzal Dosage

Dosage for a sore throat, runny nose, and eye irritation

Adult (12 years and older)
  • Recommended: 5 mg once daily in the evening
  • Maximum: 5 mg once daily in the evening
Children (6 - 11 years)
  • Recommended: 2.5 mg once daily in the evening
  • Maximum: 2.5 mg once daily in the evening
Older Adults
  • Recommended: 5 mg once daily in the evening

Dosage for severe allergies

Adult (12 years and older)
  • Recommended: 5 mg once daily in the evening
Children (6 - 11 years)
  • Recommended: 2.5 mg once daily in the evening
  • Maximum: 2.5 mg once daily in the evening
Older Adults
  • Recommended: 2.5 mg once daily in the evening

Minimum Age

6 years

Dosage calculation for children

To calculate the dosage for children please use the weight based dose calculator to calculate the appropriate dosage as per the weight of your child.


Strength: 5 mg
Oral solution
Strength: 0.5 mg/mL

Special Instructions

Dosage for minor kidney issues
In this condition, the recommended dose is 2.5 mg once a day.
Dosage for moderate kidney issues
In this condition, the recommended dose is 2.5 mg once every two days.
Dosage for severe kidney issues
In this condition, the recommended dose is 2.5 mg once every three days.
Take this medicine in a single dose.
Oral solution
Take this oral solution daily without regard to meals.

Missed Dose

Skip the missed dose and take the next dose as per your regular schedule.


What to do if you overdose on Xyzal?
No specific solution is known to cancel the effects of an overdose of Xyzal.
Symptoms of an overdose of Xyzal
If you use too much of this medicine, it could lead to dangerous levels of the medicine in your body. In such cases, symptoms of an overdose may include:
  • agitation
  • drowsiness
  • restlessness
If you think you have overdosed on Xyzal Tablet, call a poison control center immediately. You can look up the poison control center information from the Poison Center Finder at

Precautions while using Xyzal

Before you use Xyzal, tell your doctor of your medical and health history including the following:
The risk of side-effects is higher in patients with kidney disease.
Before you use Xyzal Tablet, discuss with your doctor if you are allergic to it or its ingredients. Your doctor may prescribe an alternative medicine and update your medical records to record this information.
The use of this medicine may change function of the kidneys. If you have a kidney disease, the functioning of your kidneys should be monitored regularly.


Xyzal Tablet can make you feel sleepy. Be careful when using any machinery, driving a vehicle, or doing any other activity that needs you to be fully alert. The consumption of alcohol with Xyzal Tablet can worsen the sleepiness.

Use in Pregnancy

The use of Xyzal during pregnancy should only be when required.

Use while Breastfeeding

The use of Xyzal Tablet is not safe for use in women who are breastfeeding. If you are breastfeeding a baby, discuss with your doctor if you should either discontinue breastfeeding or stop using this medicine while breastfeeding. This medicine may pass into breast milk and hence use in mothers who breastfeed is not recommended.

Use while Conceiving

It is not known if this medicine is safe for use in women who are conceiving. Consult with your doctor before you use Xyzal.


Avoid consuming alcohol together with Xyzal. Drinking alcohol may cause with Xyzal leads to a reduction in alertness and can cause accidents if you are driving, operating any machine, or any other activity that requires full mental awareness.

Xyzal Side-effects

The following side-effects may commonly occur when using Xyzal Tablet. If any of these side-effects worsen or last for a long time, you should consult with your doctor:
The following side-effects may commonly occur in children when using Xyzal Tablet. Discuss with your doctor if any of these side-effects last for a long time or are severe:
Rarely, the use of Xyzal Tablet may cause the following side-effects:
  • abnormal liver function
  • confusion
  • depression
  • feeling of anger
  • hallucination
  • increase in the rate of the heartbeat
  • painful urination
  • sleeplessness
  • swelling from excessive accumulation of fluid in tissues
  • uncontrollable body movements
  • uncontrolled urination
The following severe side-effects may also occur when using Xyzal Tablet:
  • Life-threatening allergic reaction
    Symptoms: irritation in the eyes, swelling in the throat shortness of breath
Your doctor has prescribed this Xyzal because they have judged that the benefits outweigh the risks posed by side-effects. Many people using this medicine do not have serious side-effects. This is not a complete list of possible side-effects for Xyzal.
If you experience side-effects or notice other side-effects not listed above, contact your doctor for medical advice. You may also report side-effects to your local food and drug administration authority. You can look up the drug authority contact information from the Drug Authority Finder at


Central Nervous System Depressants

Patients using medicines called as "central nervous system depressants" are at an increased risk when using this medicine. These patients may have a reduction in alertness. Such patients should be monitored closely for these changes.

Alcohol Consumption

Patients who drink alcohol are at an increased risk when using this medicine. Reduction in alertness can happen when using Xyzal with alcohol. As a result, this medicine should not be used in patients who drink alcohol.

Hazardous Occupations

Patients engaged in hazardous occupations are at an increased risk when using this medicine as this medicine causes you to feel tired, drowsy, and sleepy. Patients should not drive, or use machines, or get involved in activities that require mental alertness while using this medicine.

Interactions with Xyzal

When two or more medicines are taken together, it can change how the medicines work and increase the risk of side-effects. In medical terms, this is called as a Drug Interaction.
This page does not contain all the possible interactions of Xyzal Tablet. Share a list of all medicines that you use with your doctor and pharmacist. Do not start, stop, or change the dose of any medicines without the approval of your doctor.

Xanthine Derivatives

Xyzal Tablet may interact with theophylline, which is used to treat asthma and other lung related problems. Theophylline reduces the removal of Xyzal from the body. This can increase the effects of Xyzal on the bidy.

Antiviral Drugs

There may be an interaction of Xyzal with ritonavir, which is used to treat HIV infections. Ritonavir decreases the removal of Xyzal from the body. This can increase the effects of Xyzal on the body.

Central Nervous System Depressants

Xyzal Tablet interacts with central nervous system depressants which are used to slow down the brain activities. Using Xyzal with brain depressants may lead to a greater reduction in mental awareness.


Special instructions need to be followed while taking this medicine along with cetrizine, which is used to treat allergies. Xyzal increases the effects of cetrizine on the body.

Expired Medication

Taking a single dose of expired Xyzal is unlikely to cause a side-effect. However, please discuss with your doctor or pharmacist, if you feel unwell or sick. An expired medicine may become ineffective in treating your prescribed conditions. To be on the safe side, it is important not to use an expired drug. You are much safer by always keeping a fresh supply of unexpired medicines.

Safe Disposal of Medication

  • If there are disposal instructions on the package, please follow the instructions.
  • If there are medicine take-back programs in your country, you should contact the respective authority to arrange for the disposal of the medicine. For example, in the USA, the Drug Enforcement Administration regularly hosts National Prescription Drug Take-Back events.
  • If there are no take-back programs, mix the medicine with dirt and place them in a sealed plastic bag. Throw the plastic bag in your household trash. Separately, remove all personal information including the prescription label from the medicine packaging and then dispose off the container.
  • If specifically indicated on the medicine package that it needs to be flushed down the toilet when no longer needed, perform the required step.

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